The effect of BW upon the operational performance of a tubular ceramic membrane was investigated for the MF of a high solids content (15 wt %) MPI feed inoculated with Bacillus mycoides spores. Three tubular ceramic Membralox™ (Pall Filtration, Bazet, France) MF membranes of pore sizes 0.8, 2.0 and 12.0μm pore diameters were tested. A 10-s backflush every 5min was found to be the most effective protocol during filtration experiments. Membrane cleaning using a combination of a long rinsing backflush at 1 bar, and acid and alkali steps without BW were found to be most effective after MPI filtration. Application of this protocol resulted in a flux recovery of 99.6%.