Autoantigen glycoprotein 70 expression is regulated by a single locus, which acts as a checkpoint for pathogenic anti-glycoprotein 70 autoantibody production and hence for the corresponding development of severe nephritis, in lupus-prone PXSB mice.

ME Haywood, TJ Vyse, A McDermott, EM Thompson, A Ida, MJ Walport, S Izui, Bernard J Morley

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Immunology and Microbiology