Attention bias modification training for adolescents with chronic pain: A randomized placebo-controlled trial

Lauren C. Heathcote, Konrad Jacobs, Dimitri M L Van Ryckeghem, Emma Fisher, Christopher Eccleston, Elaine Fox, Jennifer Y F Lau

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Attention bias for pain-related information is theorised to maintain chronic pain, indicating that changing this bias could improve pain-related outcomes. Modifying attention biases in adolescents, when chronic pain often first emerges, may be particularly beneficial. We report here a randomized, placebo-controlled, parallel-group trial of attention bias modification (ABM) training in adolescents with chronic noncancer pain. Adolescent patients (N = 66) were randomly assigned to complete multiple sessions of dot-probe ABM training (N = 23), placebo training (N = 22), or no training (waitlist; N = 21) across a period of 4 weeks. Patients completed all assessments at a hospital-based pediatric pain clinic and completed all training at home. We examined the relative effects of ABM on attention bias and attention control, as well as pain symptomatology (primary outcome), pain catastrophizing, anxiety and depression symptoms, and functional disability (secondary outcomes) immediately after training and 3 months later. We found no evidence that ABM changed attention bias or attention control in comparison with placebo training or no training. We also found that pain and pain-related outcomes were no different for those undergoing ABM compared with placebo training or no training when tested immediately after training or 3 months later. Overall, we found no evidence to support the efficacy of dot-probe ABM for improving pain-related outcomes in adolescents with chronic pain. This study was registered on the NIHR Clinical Research Network Portfolio in August 2014 (UK Clinical Trials Gateway: CPMS 17251) and funded by a Research Training Fellowship awarded to Lauren Heathcote by Action Medical Research for Children.

LanguageEnglish
Pages239-251
Number of pages13
JournalPain
Volume159
Issue number2
Early online date29 Sep 2017
DOIs
StatusPublished - 1 Feb 2018

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Chronic Pain
Randomized Controlled Trials
Placebos
Pain
Catastrophization
Anxiety
Psychological Models
Depression
Pain Threshold
Aptitude
Acute Pain

Keywords

  • Attention bias modification
  • Cognitive bias
  • Pediatric chronic pain
  • Randomized controlled trial

ASJC Scopus subject areas

  • Neurology
  • Clinical Neurology
  • Anesthesiology and Pain Medicine

Cite this

Attention bias modification training for adolescents with chronic pain: A randomized placebo-controlled trial. / Heathcote, Lauren C.; Jacobs, Konrad; Van Ryckeghem, Dimitri M L; Fisher, Emma; Eccleston, Christopher; Fox, Elaine; Lau, Jennifer Y F.

In: Pain, Vol. 159, No. 2, 01.02.2018, p. 239-251.

Research output: Contribution to journalArticle

Heathcote, Lauren C. ; Jacobs, Konrad ; Van Ryckeghem, Dimitri M L ; Fisher, Emma ; Eccleston, Christopher ; Fox, Elaine ; Lau, Jennifer Y F. / Attention bias modification training for adolescents with chronic pain: A randomized placebo-controlled trial. In: Pain. 2018 ; Vol. 159, No. 2. pp. 239-251.
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