Atomistic insight into the origin of the temperature-dependence of kinetic isotope effects and H-tunnelling in enzyme systems is revealed through combined experimental studies and biomolecular simulation

Sam Hay, Christopher Pudney, Parvinder Hothi, Linus O Johannissen, Laura Masgrau, Jiayun Pang, David Leys, Michael J Sutcliffe, Nigel S Scrutton

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