Asymmetrical hip loading correlates with metal ion levels in patients with metal-on-metal hip resurfacing during sit-to-stand

Stephen Mellon, George Grammatopoulos, Hemant Pandit, David W Murray, Harinderjit S Gill

Research output: Contribution to journalArticle

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Abstract

The occurrence of pseudotumours following metal-on-metal hip resurfacing arthroplasty (MoMHRA) has been associated with high serum metal ion levels and consequently higher than normal bearing wear. Measuring ground reaction force is a simple method of collecting information on joint loading during a sit-to-stand (STS). We investigated vertical ground reaction force (VGRF) asymmetry during sit-to-stand for 12 MoMHRA patients with known serum metal ion levels. Asymmetry was assessed using two methods: a ratio of VGRF for implanted/unimplanted side and an absolute symmetry index (ASI). It was found that subjects with high serum metal ion levels preferentially loaded their implanted sides. The difference between the two groups was most apparent during the first 22% of STS. VGRF ratio showed significant and strong correlation with serum metal ion levels (Spearman's rho = 0.8, p = 0.003). These results suggest that individual activity patterns play a role in the wear of MoMHRA and preferential loading of an implanted limb during the initiation of motion may increase the wear of metal-on-metal hip replacements.
Original languageEnglish
Pages (from-to)20-26
Number of pages7
JournalHip International
Volume24
Issue number1
Early online date22 Jan 2014
DOIs
Publication statusPublished - Jan 2014

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Metals
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Arthroplasty
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Joints

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Asymmetrical hip loading correlates with metal ion levels in patients with metal-on-metal hip resurfacing during sit-to-stand. / Mellon, Stephen; Grammatopoulos, George; Pandit, Hemant; Murray, David W; Gill, Harinderjit S.

In: Hip International, Vol. 24, No. 1, 01.2014, p. 20-26.

Research output: Contribution to journalArticle

Mellon, Stephen ; Grammatopoulos, George ; Pandit, Hemant ; Murray, David W ; Gill, Harinderjit S. / Asymmetrical hip loading correlates with metal ion levels in patients with metal-on-metal hip resurfacing during sit-to-stand. In: Hip International. 2014 ; Vol. 24, No. 1. pp. 20-26.
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