Asymmetric palladium catalyzed allylic substitution using phosphorus containing oxazoline ligands

G.J. Dawson, C.G. Frost, Jonathan M J Williams, S.J. Coote

Research output: Contribution to journalArticle

Abstract

A series of new phosphorus-containing oxazoline ligands has been developed. The use of these ligands for asymmetric palladium catalysed allylic substitution of 1,3-diphenylprop-2-enyl-1-acetate 12 with the sodium salt of dimethylmalonate has been achieved with 90-94% ee and 88-99% yield.
Original languageEnglish
Pages (from-to)3149-3150
Number of pages2
JournalTetrahedron Letters
Volume34
Issue number19
DOIs
Publication statusPublished - 7 May 1993

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