Asymmetric palladium catalyzed allylic substitution using phosphorus containing oxazoline ligands

G.J. Dawson, C.G. Frost, Jonathan M J Williams, S.J. Coote

Research output: Contribution to journalArticle

Abstract

A series of new phosphorus-containing oxazoline ligands has been developed. The use of these ligands for asymmetric palladium catalysed allylic substitution of 1,3-diphenylprop-2-enyl-1-acetate 12 with the sodium salt of dimethylmalonate has been achieved with 90-94% ee and 88-99% yield.
LanguageEnglish
Pages3149-3150
Number of pages2
JournalTetrahedron Letters
Volume34
Issue number19
DOIs
StatusPublished - 7 May 1993

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Palladium
Phosphorus
Substitution reactions
Ligands
Acetates
Salts
Sodium

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Asymmetric palladium catalyzed allylic substitution using phosphorus containing oxazoline ligands. / Dawson, G.J.; Frost, C.G.; Williams, Jonathan M J; Coote, S.J.

In: Tetrahedron Letters, Vol. 34, No. 19, 07.05.1993, p. 3149-3150.

Research output: Contribution to journalArticle

Dawson, G.J. ; Frost, C.G. ; Williams, Jonathan M J ; Coote, S.J. / Asymmetric palladium catalyzed allylic substitution using phosphorus containing oxazoline ligands. In: Tetrahedron Letters. 1993 ; Vol. 34, No. 19. pp. 3149-3150.
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