Associations between cardiorespiratory fitness and C-reactive protein in men

T S Church, C E Barlow, Conrad P Earnest, J B Kampert, E L Priest, S N Blair

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269 Citations (Scopus)

Abstract

OBJECTIVE: This study examined the association between cardiorespiratory fitness and C-reactive protein (CRP), with adjustment for weight and within weight categories. METHODS AND RESULTS: We calculated median and adjusted geometric mean CRP levels, percentages of individuals with an elevated CRP (> or =2.00 mg/L), and odds ratios of elevated CRP across 5 levels of cardiorespiratory fitness for 722 men. CRP values were adjusted for age, body mass index, vitamin use, statin medication use, aspirin use, the presence of inflammatory disease, cardiovascular disease, and diabetes, and smoking habit. We found an inverse association of CRP across fitness levels (P for trend
Original languageEnglish
Pages (from-to)1869-1876
Number of pages8
JournalArteriosclerosis, thrombosis, and vascular biology
Volume22
Issue number11
DOIs
Publication statusPublished - 2002

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Keywords

  • Respiratory System/*metabolism
  • Human
  • Body Mass Index
  • Exercise
  • Longitudinal Studies
  • U.S. Gov't
  • Obesity/epidemiology
  • Diabetes Mellitus/epidemiology
  • Body Weight/physiology
  • P.H.S.
  • Support
  • Cardiovascular Diseases/epidemiology/prevention & control
  • Risk Factors
  • Cardiovascular System/*metabolism
  • C-Reactive Protein/*metabolism
  • Middle Age
  • Physical Fitness/*physiology
  • Male

Cite this

Church, T. S., Barlow, C. E., Earnest, C. P., Kampert, J. B., Priest, E. L., & Blair, S. N. (2002). Associations between cardiorespiratory fitness and C-reactive protein in men. Arteriosclerosis, thrombosis, and vascular biology, 22(11), 1869-1876. https://doi.org/10.1161/​01.ATV.0000036611.77940.F8