Assessment of nicotine replacement therapy for harm reduction in smokers: an n-of-1 study

Maddy Dyer; Christopher J Stone; Suzanne McDonald; James McGree; Andy Skinner; Kate Tilling; George D Smith; Angela S Attwood; Marcus R Munafo

doi:10.17605/OSF.IO/8WMVY

Assessment of nicotine replacement therapy for harm reduction in smokers: an n-of-1 study

Maddy Dyer, Christopher J Stone, Suzanne McDonald, James McGree, Andy Skinner, Kate Tilling, George D Smith, Angela S Attwood, Marcus R Munafo

Vice Chancellor's Office

Research output: Other contribution

Abstract

The primary aim of this study is to compare the effect of active nicotine replacement therapy patches with placebo patches on (1) smoking urges, and (2) number of smoking drags, in a sample of adult daily smokers. This is a remote experimental study lasting 58 days and it uses an N-of-1 design (each participant acts as his or her own control). Participants are randomly assigned to one of two sequence conditions (ABCCBCBBC or ACBBCBCCB), where A is the baseline period, B is an active treatment period and C is a placebo period.

Original language	English
Publisher	Open Science Framework (OSF)
DOIs	https://doi.org/10.17605/OSF.IO/8WMVY
Publication status	Published - 7 Oct 2022

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https://osf.io/asvbdLicence: CC BY

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title = "Assessment of nicotine replacement therapy for harm reduction in smokers: an n-of-1 study",

abstract = "The primary aim of this study is to compare the effect of active nicotine replacement therapy patches with placebo patches on (1) smoking urges, and (2) number of smoking drags, in a sample of adult daily smokers. This is a remote experimental study lasting 58 days and it uses an N-of-1 design (each participant acts as his or her own control). Participants are randomly assigned to one of two sequence conditions (ABCCBCBBC or ACBBCBCCB), where A is the baseline period, B is an active treatment period and C is a placebo period.",

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AU - McDonald, Suzanne

AU - McGree, James

AU - Skinner, Andy

AU - Tilling, Kate

AU - Smith, George D

AU - Attwood, Angela S

AU - Munafo, Marcus R

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N2 - The primary aim of this study is to compare the effect of active nicotine replacement therapy patches with placebo patches on (1) smoking urges, and (2) number of smoking drags, in a sample of adult daily smokers. This is a remote experimental study lasting 58 days and it uses an N-of-1 design (each participant acts as his or her own control). Participants are randomly assigned to one of two sequence conditions (ABCCBCBBC or ACBBCBCCB), where A is the baseline period, B is an active treatment period and C is a placebo period.

AB - The primary aim of this study is to compare the effect of active nicotine replacement therapy patches with placebo patches on (1) smoking urges, and (2) number of smoking drags, in a sample of adult daily smokers. This is a remote experimental study lasting 58 days and it uses an N-of-1 design (each participant acts as his or her own control). Participants are randomly assigned to one of two sequence conditions (ABCCBCBBC or ACBBCBCCB), where A is the baseline period, B is an active treatment period and C is a placebo period.

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M3 - Other contribution

PB - Open Science Framework (OSF)

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Assessment of nicotine replacement therapy for harm reduction in smokers: an n-of-1 study

Abstract

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