Assessing Cellular Response to Functionalized α-Helical Peptide Hydrogels

N Mehrban, ES Abelardo, A Wasmuth, K Hudson, LM Mullen, AR Thomson, MA Birchall, DN Woolfson

Research output: Contribution to journalArticlepeer-review

28 Citations (SciVal)

Abstract

α-Helical peptide hydrogels are decorated with a cell-binding peptide motif (RGDS), which is shown to promote adhesion, proliferation, and differentiation of PC12 cells. Gel structure and integrity are maintained after functionalization. This opens possibilities for the bottom-up design and engineering of complex functional scaffolds for 2D and 3D cell cultures.
Original languageEnglish
Pages (from-to)1387-1391
JournalAdvanced Healthcare Materials
Volume3
DOIs
Publication statusPublished - 24 Mar 2014
Externally publishedYes

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