Assessing Cellular Response to Functionalized α-Helical Peptide Hydrogels

N Mehrban; ES Abelardo; A Wasmuth; K Hudson; LM Mullen; AR Thomson; MA Birchall; DN Woolfson

doi:10.1002/adhm.201400065

Assessing Cellular Response to Functionalized α-Helical Peptide Hydrogels

N Mehrban, ES Abelardo, A Wasmuth, K Hudson, LM Mullen, AR Thomson, MA Birchall, DN Woolfson

Research output: Contribution to journal › Article › peer-review

33 Citations (SciVal)

Abstract

α-Helical peptide hydrogels are decorated with a cell-binding peptide motif (RGDS), which is shown to promote adhesion, proliferation, and differentiation of PC12 cells. Gel structure and integrity are maintained after functionalization. This opens possibilities for the bottom-up design and engineering of complex functional scaffolds for 2D and 3D cell cultures.

Original language	English
Pages (from-to)	1387-1391
Journal	Advanced Healthcare Materials
Volume	3
DOIs	https://doi.org/10.1002/adhm.201400065
Publication status	Published - 24 Mar 2014
Externally published	Yes

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title = "Assessing Cellular Response to Functionalized α-Helical Peptide Hydrogels",

abstract = "α-Helical peptide hydrogels are decorated with a cell-binding peptide motif (RGDS), which is shown to promote adhesion, proliferation, and differentiation of PC12 cells. Gel structure and integrity are maintained after functionalization. This opens possibilities for the bottom-up design and engineering of complex functional scaffolds for 2D and 3D cell cultures.",

author = "N Mehrban and ES Abelardo and A Wasmuth and K Hudson and LM Mullen and AR Thomson and MA Birchall and DN Woolfson",

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AU - Mehrban, N

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AU - Wasmuth, A

AU - Hudson, K

AU - Mullen, LM

AU - Thomson, AR

AU - Birchall, MA

AU - Woolfson, DN

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AB - α-Helical peptide hydrogels are decorated with a cell-binding peptide motif (RGDS), which is shown to promote adhesion, proliferation, and differentiation of PC12 cells. Gel structure and integrity are maintained after functionalization. This opens possibilities for the bottom-up design and engineering of complex functional scaffolds for 2D and 3D cell cultures.

U2 - 10.1002/adhm.201400065

DO - 10.1002/adhm.201400065

M3 - Article

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JO - Advanced Healthcare Materials

JF - Advanced Healthcare Materials

ER -

Assessing Cellular Response to Functionalized α-Helical Peptide Hydrogels

Abstract

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