Application of a structured multifunctional reactor for the oxidation of a liquid organic feedstock

Pawel K Plucinski, Dmitry V Bavykin, Stan T Kolaczkowski, Alexei A Lapkin

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

Expts. are performed in a structured packed bed reactor that was developed for the selective oxidn. of org. liqs. to produce pharmaceutical products. Mol. oxygen is used as the oxidant, providing a "cleaner processing route", than in established methods. The structured assembly consists of an integrated heat exchange system, a gas/liq. mixing zone, and provision for reactant injection. To illustrate the application, the selective oxidn. of benzyl alc. to benzaldehyde was studied. The reactor consisted of parallel reaction channels (10 cm long and square shaped) that were packed with Ru/Al2O3 (0.9 wt% Ru) catalyst particles. From expts. in three different sizes of channel: 2 mm * 2 mm, 3 mm * 3 mm, and 5 mm * 5 mm (at P = 8 bar, T = 388 K, with liq. and gas flows L = 3.2 kg m-2 s-1, G = 1.35 * 10-2 kg m-2 s-1), in a short 10 cm length of channel, a product yield up to ca. 29% (with min. 99.5% selectivity) could be obtained. Conversions were highest in the 3 mm * 3 mm channel. From the expts. with the reactor mounted both in horizontal and vertical planes, gravitational influences are minor. The choice of solvent was shown to affect the yield of benzaldehyde. The highest yield was with toluene; the application of dioxane/water mixt. (70/30 by vol.) and N-Me pyrrolidone (NMP) not only decreased the yield by factor 2, but NMP also caused deactivation of the catalyst. Preliminary results are presented of work with Pt/C (Pt 3 wt%) catalyst. [on SciFinder (R)]
Original languageEnglish
Pages (from-to)479-483
Number of pages5
JournalCatalysis Today
Volume105
Issue number3-4
Publication statusPublished - 2005

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Feedstocks
Pyrrolidinones
Oxidation
Catalysts
Liquids
Toluene
Packed beds
Oxidants
Drug products
Flow of gases
Gases
Oxygen
Water
Processing
Pharmaceutical Preparations
benzaldehyde
Hot Temperature
1,4-dioxane

Keywords

  • Solvent effect (application of a structured multifunctional packed bed reactor for oxidn. of a liq. org. feedstock)
  • Oxidation
  • selective oxidn benzyl alc benzaldehyde ruthenium catalyst
  • structured packed bed reactor oxidn liq org feedstock
  • Reactors (packed-bed
  • Oxidation catalysts (selective
  • application of a structured multifunctional packed bed reactor for oxidn. of a liq. org. feedstock)

Cite this

Application of a structured multifunctional reactor for the oxidation of a liquid organic feedstock. / Plucinski, Pawel K; Bavykin, Dmitry V; Kolaczkowski, Stan T; Lapkin, Alexei A.

In: Catalysis Today, Vol. 105, No. 3-4, 2005, p. 479-483.

Research output: Contribution to journalArticle

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AU - Plucinski, Pawel K

AU - Bavykin, Dmitry V

AU - Kolaczkowski, Stan T

AU - Lapkin, Alexei A

PY - 2005

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N2 - Expts. are performed in a structured packed bed reactor that was developed for the selective oxidn. of org. liqs. to produce pharmaceutical products. Mol. oxygen is used as the oxidant, providing a "cleaner processing route", than in established methods. The structured assembly consists of an integrated heat exchange system, a gas/liq. mixing zone, and provision for reactant injection. To illustrate the application, the selective oxidn. of benzyl alc. to benzaldehyde was studied. The reactor consisted of parallel reaction channels (10 cm long and square shaped) that were packed with Ru/Al2O3 (0.9 wt% Ru) catalyst particles. From expts. in three different sizes of channel: 2 mm * 2 mm, 3 mm * 3 mm, and 5 mm * 5 mm (at P = 8 bar, T = 388 K, with liq. and gas flows L = 3.2 kg m-2 s-1, G = 1.35 * 10-2 kg m-2 s-1), in a short 10 cm length of channel, a product yield up to ca. 29% (with min. 99.5% selectivity) could be obtained. Conversions were highest in the 3 mm * 3 mm channel. From the expts. with the reactor mounted both in horizontal and vertical planes, gravitational influences are minor. The choice of solvent was shown to affect the yield of benzaldehyde. The highest yield was with toluene; the application of dioxane/water mixt. (70/30 by vol.) and N-Me pyrrolidone (NMP) not only decreased the yield by factor 2, but NMP also caused deactivation of the catalyst. Preliminary results are presented of work with Pt/C (Pt 3 wt%) catalyst. [on SciFinder (R)]

AB - Expts. are performed in a structured packed bed reactor that was developed for the selective oxidn. of org. liqs. to produce pharmaceutical products. Mol. oxygen is used as the oxidant, providing a "cleaner processing route", than in established methods. The structured assembly consists of an integrated heat exchange system, a gas/liq. mixing zone, and provision for reactant injection. To illustrate the application, the selective oxidn. of benzyl alc. to benzaldehyde was studied. The reactor consisted of parallel reaction channels (10 cm long and square shaped) that were packed with Ru/Al2O3 (0.9 wt% Ru) catalyst particles. From expts. in three different sizes of channel: 2 mm * 2 mm, 3 mm * 3 mm, and 5 mm * 5 mm (at P = 8 bar, T = 388 K, with liq. and gas flows L = 3.2 kg m-2 s-1, G = 1.35 * 10-2 kg m-2 s-1), in a short 10 cm length of channel, a product yield up to ca. 29% (with min. 99.5% selectivity) could be obtained. Conversions were highest in the 3 mm * 3 mm channel. From the expts. with the reactor mounted both in horizontal and vertical planes, gravitational influences are minor. The choice of solvent was shown to affect the yield of benzaldehyde. The highest yield was with toluene; the application of dioxane/water mixt. (70/30 by vol.) and N-Me pyrrolidone (NMP) not only decreased the yield by factor 2, but NMP also caused deactivation of the catalyst. Preliminary results are presented of work with Pt/C (Pt 3 wt%) catalyst. [on SciFinder (R)]

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KW - structured packed bed reactor oxidn liq org feedstock

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KW - Oxidation catalysts (selective

KW - application of a structured multifunctional packed bed reactor for oxidn. of a liq. org. feedstock)

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SP - 479

EP - 483

JO - Catalysis Today

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SN - 0920-5861

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