Abstract
Polymorphism is known as the ability of a compound to exist in more than one crystalline structure, and is very common in the crystallization of active pharmaceutical ingredients (APIs). Polymorph screening is fundamental during the development of new drugs since the formation of the wrong polymorph can affect solubility, rate of dissolution and toxicity of the API, therefore, seriously threatening the life of patients [1]. This work reports a novel microfluidic method for studying polymorphism based on multiplex fluoropolymer microfluidic devices.
Original language | English |
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Title of host publication | 20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016 |
Publisher | Chemical and Biological Microsystems Society |
Pages | 910-911 |
Number of pages | 2 |
ISBN (Electronic) | 9780979806490 |
Publication status | Published - 1 Jan 2016 |
Event | 20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016 - Dublin, Ireland Duration: 9 Oct 2016 → 13 Oct 2016 |
Conference
Conference | 20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016 |
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Country/Territory | Ireland |
City | Dublin |
Period | 9/10/16 → 13/10/16 |
Funding
This work is funded through the European Research Council grant no. [280106-CrySys].
Keywords
- Crystallization
- Micro capillary film
- Polymorph screening
ASJC Scopus subject areas
- Control and Systems Engineering