It is difficult but not impossible to determine a macromolecular structure using X-ray data obtained from twinned crystals, providing it is noticed and corrected. For perfectly twinned crystals, the structure can probably only be solved by molecular replacement. It is possible to detect and characterize twinning from an analysis of the intensity statistics and crystal packing density. Tables of likely twinning operators and some examples are discussed here.
|Number of pages||9|
|Journal||Acta Crystallographica Section D: Biological Crystallography|
|Publication status||Published - 1 Oct 1999|
ASJC Scopus subject areas
- Structural Biology