An experimental investigation of factors involved in the decision to undertake genetic testing for schizophrenia

Paul M Salkovskis, Katharine A Rimes, J Bolton, A L Wroe

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

Background : The psychological issues surrounding genetic testing, particularly decision-making processes, are not well understood. Previous studies suggest that apparently “nondirective” strategies intended to help individuals consider the consequences of undergoing predictive testing for physical illness can influence the decision.
Aims: To investigate the influence of selectively focussing on different aspects of previously provided information concerning genetic testing for schizophrenia.
Method: Community participants (n = 120) rated how likely they would be to arrange to have a genetic test for schizophrenia if it were available, before and after being given detailed information about schizophrenia and the implications of testing. Participants were then randomly allocated to four groups, and were implicitly focused on the negative issues (negative group), the positive issues (positive group), both the negative and positive issues (all-focusing group) or schizophrenia-irrelevant health-related issues (control group). All issues on which the experimental groups focussed were included in the information provided and the form of questioning meets current definitions of nondirectiveness.
Results: Hypothetical decisions whether to arrange a genetic test for schizophrenia were influenced by the issues on which participants had focused; the positive group were more likely to say they would be tested relative to the other groups.
Conclusions: Decisions about genetic testing for schizophrenia were influenced by the specific issues on which individuals were encouraged to focus at that time.
Original languageEnglish
Pages (from-to)202-210
Number of pages9
JournalJournal of Mental Health
Volume19
Issue number2
DOIs
Publication statusPublished - 2010

Fingerprint

Genetic Testing
Schizophrenia
Decision Making
Psychology
Control Groups
Health

Keywords

  • Schizophrenia
  • stigma
  • schizophrenia decision making
  • experimental study
  • genetic testing

Cite this

An experimental investigation of factors involved in the decision to undertake genetic testing for schizophrenia. / Salkovskis, Paul M; Rimes, Katharine A; Bolton, J; Wroe, A L.

In: Journal of Mental Health, Vol. 19, No. 2, 2010, p. 202-210.

Research output: Contribution to journalArticle

@article{f5f22c1e9a84400cb364b4f73b6c2439,
title = "An experimental investigation of factors involved in the decision to undertake genetic testing for schizophrenia",
abstract = "Background : The psychological issues surrounding genetic testing, particularly decision-making processes, are not well understood. Previous studies suggest that apparently “nondirective” strategies intended to help individuals consider the consequences of undergoing predictive testing for physical illness can influence the decision. Aims: To investigate the influence of selectively focussing on different aspects of previously provided information concerning genetic testing for schizophrenia. Method: Community participants (n = 120) rated how likely they would be to arrange to have a genetic test for schizophrenia if it were available, before and after being given detailed information about schizophrenia and the implications of testing. Participants were then randomly allocated to four groups, and were implicitly focused on the negative issues (negative group), the positive issues (positive group), both the negative and positive issues (all-focusing group) or schizophrenia-irrelevant health-related issues (control group). All issues on which the experimental groups focussed were included in the information provided and the form of questioning meets current definitions of nondirectiveness. Results: Hypothetical decisions whether to arrange a genetic test for schizophrenia were influenced by the issues on which participants had focused; the positive group were more likely to say they would be tested relative to the other groups. Conclusions: Decisions about genetic testing for schizophrenia were influenced by the specific issues on which individuals were encouraged to focus at that time.",
keywords = "Schizophrenia, stigma, schizophrenia decision making, experimental study, genetic testing",
author = "Salkovskis, {Paul M} and Rimes, {Katharine A} and J Bolton and Wroe, {A L}",
year = "2010",
doi = "10.3109/09638230903469160",
language = "English",
volume = "19",
pages = "202--210",
journal = "Journal of Mental Health",
issn = "0963-8237",
publisher = "Informa Healthcare",
number = "2",

}

TY - JOUR

T1 - An experimental investigation of factors involved in the decision to undertake genetic testing for schizophrenia

AU - Salkovskis, Paul M

AU - Rimes, Katharine A

AU - Bolton, J

AU - Wroe, A L

PY - 2010

Y1 - 2010

N2 - Background : The psychological issues surrounding genetic testing, particularly decision-making processes, are not well understood. Previous studies suggest that apparently “nondirective” strategies intended to help individuals consider the consequences of undergoing predictive testing for physical illness can influence the decision. Aims: To investigate the influence of selectively focussing on different aspects of previously provided information concerning genetic testing for schizophrenia. Method: Community participants (n = 120) rated how likely they would be to arrange to have a genetic test for schizophrenia if it were available, before and after being given detailed information about schizophrenia and the implications of testing. Participants were then randomly allocated to four groups, and were implicitly focused on the negative issues (negative group), the positive issues (positive group), both the negative and positive issues (all-focusing group) or schizophrenia-irrelevant health-related issues (control group). All issues on which the experimental groups focussed were included in the information provided and the form of questioning meets current definitions of nondirectiveness. Results: Hypothetical decisions whether to arrange a genetic test for schizophrenia were influenced by the issues on which participants had focused; the positive group were more likely to say they would be tested relative to the other groups. Conclusions: Decisions about genetic testing for schizophrenia were influenced by the specific issues on which individuals were encouraged to focus at that time.

AB - Background : The psychological issues surrounding genetic testing, particularly decision-making processes, are not well understood. Previous studies suggest that apparently “nondirective” strategies intended to help individuals consider the consequences of undergoing predictive testing for physical illness can influence the decision. Aims: To investigate the influence of selectively focussing on different aspects of previously provided information concerning genetic testing for schizophrenia. Method: Community participants (n = 120) rated how likely they would be to arrange to have a genetic test for schizophrenia if it were available, before and after being given detailed information about schizophrenia and the implications of testing. Participants were then randomly allocated to four groups, and were implicitly focused on the negative issues (negative group), the positive issues (positive group), both the negative and positive issues (all-focusing group) or schizophrenia-irrelevant health-related issues (control group). All issues on which the experimental groups focussed were included in the information provided and the form of questioning meets current definitions of nondirectiveness. Results: Hypothetical decisions whether to arrange a genetic test for schizophrenia were influenced by the issues on which participants had focused; the positive group were more likely to say they would be tested relative to the other groups. Conclusions: Decisions about genetic testing for schizophrenia were influenced by the specific issues on which individuals were encouraged to focus at that time.

KW - Schizophrenia

KW - stigma

KW - schizophrenia decision making

KW - experimental study

KW - genetic testing

UR - http://www.scopus.com/inward/record.url?scp=77950851998&partnerID=8YFLogxK

UR - http://dx.doi.org/10.3109/09638230903469160

U2 - 10.3109/09638230903469160

DO - 10.3109/09638230903469160

M3 - Article

VL - 19

SP - 202

EP - 210

JO - Journal of Mental Health

JF - Journal of Mental Health

SN - 0963-8237

IS - 2

ER -