An efficient synthesis of semiplenamide C

I R Davies; M Cheeseman; D G Niyadurupola; S D Bull

doi:10.1016/j.tetlet.2005.06.027

An efficient synthesis of semiplenamide C

I R Davies, M Cheeseman, D G Niyadurupola, S D Bull

Department of Chemistry

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26 Citations (SciVal)

Abstract

Semiplenamides are anandamide-like fatty acid amide metabolites previously isolated from a marine cyanobacterium that display a range of biological activity. Novel syn-aldol/dehydration methodology has been developed for the stereoselective synthesis of the core (E)-alpha, beta-unsaturated amide functionality of this class of natural product, and employed for the efficient synthesis of semi-plenamide C. (c) 2005 Elsevier Ltd. All rights reserved.

Original language	English
Pages (from-to)	5547-5549
Number of pages	3
Journal	Tetrahedron Letters
Volume	46
Issue number	33
DOIs	https://doi.org/10.1016/j.tetlet.2005.06.027
Publication status	Published - 2005

Bibliographical note

ID number: ISI:000230879300027

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This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/j.tetlet.2005.06.027

Cite this

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AU - Cheeseman, M

AU - Niyadurupola, D G

AU - Bull, S D

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AB - Semiplenamides are anandamide-like fatty acid amide metabolites previously isolated from a marine cyanobacterium that display a range of biological activity. Novel syn-aldol/dehydration methodology has been developed for the stereoselective synthesis of the core (E)-alpha, beta-unsaturated amide functionality of this class of natural product, and employed for the efficient synthesis of semi-plenamide C. (c) 2005 Elsevier Ltd. All rights reserved.

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DO - 10.1016/j.tetlet.2005.06.027

M3 - Article

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JO - Tetrahedron Letters

JF - Tetrahedron Letters

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ER -

An efficient synthesis of semiplenamide C

Abstract

Bibliographical note

UN SDGs

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