An efficient synthesis of semiplenamide C

I R Davies, M Cheeseman, D G Niyadurupola, S D Bull

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25 Citations (SciVal)


Semiplenamides are anandamide-like fatty acid amide metabolites previously isolated from a marine cyanobacterium that display a range of biological activity. Novel syn-aldol/dehydration methodology has been developed for the stereoselective synthesis of the core (E)-alpha, beta-unsaturated amide functionality of this class of natural product, and employed for the efficient synthesis of semi-plenamide C. (c) 2005 Elsevier Ltd. All rights reserved.
Original languageEnglish
Pages (from-to)5547-5549
Number of pages3
JournalTetrahedron Letters
Issue number33
Publication statusPublished - 2005

Bibliographical note

ID number: ISI:000230879300027


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