An efficient asymmetric synthesis of cascarillic acid

M Cheeseman, S D Bull

Research output: Contribution to journalArticlepeer-review

19 Citations (SciVal)


An efficient six-step asymmetric synthesis of the cyclopropane containing natural product cascarillic acid in 41% overall yield is described. The key synthetic steps involve the use of a temporary stereogenic hydroxyl group to control the facial selectivity of a directed cyclopropanation reaction and its subsequent removal via a retro-aldol reaction.
Original languageEnglish
Pages (from-to)1119-1121
Number of pages3
Issue number7
Publication statusPublished - 2006

Bibliographical note

ID number: ISI:000237436600030


Dive into the research topics of 'An efficient asymmetric synthesis of cascarillic acid'. Together they form a unique fingerprint.

Cite this