An (E)-selective synthesis of trisubstituted (E)-alpha,beta-unsaturated acid derivatives

F J P Feuillet, Deje Robinson, S D Bull

Research output: Contribution to journalArticle

15 Citations (Scopus)

Abstract

Potassium alkoxides of N-acyloxazolidin-2-one derived syn-aldolates undergo a novel tandem intramolecular cyclisation elimination reaction to afford trisubstituted( E)-alpha,beta-unsaturated amides in high d.e., which may be converted into their corresponding acids or oxazolines in good yield.
Original languageEnglish
Pages (from-to)2184-2185
Number of pages2
JournalChemical Communications
Issue number17
DOIs
Publication statusPublished - 2003

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