An analgesiometry system for use in rabbits with some preliminary data on the effects of buprenorphine and lofentanil

R. Wootton; G. Crosst; S. Wood; C. D. Westt

doi:10.1258/002367788780746395

An analgesiometry system for use in rabbits with some preliminary data on the effects of buprenorphine and lofentanil

R. Wootton, G. Crosst, S. Wood, C. D. Westt

Research output: Contribution to journal › Article › peer-review

Abstract

A low cost infrared skin heating system has been designed to measure the efficacy of analgesics in rabbits. Following construction of a prototype, it was used to assess the effect of buprenorphine given subcutaneously and per rectum. Buprenorphine administered subcutaneously has a rapid onset of action, but its duration (8-10 h) appears slightly shorter than has been suggested previously; rectal administration appears to prolong its effect. Preliminary data show that lofentanil has a longer duration of action than buprenorphine and it may prove, therefore, to be a valuable long-acting analgesic in the rabbit.

Original language	English
Pages (from-to)	217-222
Number of pages	6
Journal	Laboratory Animals
Volume	22
Issue number	3
DOIs	https://doi.org/10.1258/002367788780746395
Publication status	Published - 1 Jul 1988

Keywords

ANALGESIOMETRY
BUPRENORPHINE
LOFENTANIL
RABBITS

ASJC Scopus subject areas

Animal Science and Zoology
General Veterinary

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10.1258/002367788780746395

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title = "An analgesiometry system for use in rabbits with some preliminary data on the effects of buprenorphine and lofentanil",

abstract = "A low cost infrared skin heating system has been designed to measure the efficacy of analgesics in rabbits. Following construction of a prototype, it was used to assess the effect of buprenorphine given subcutaneously and per rectum. Buprenorphine administered subcutaneously has a rapid onset of action, but its duration (8-10 h) appears slightly shorter than has been suggested previously; rectal administration appears to prolong its effect. Preliminary data show that lofentanil has a longer duration of action than buprenorphine and it may prove, therefore, to be a valuable long-acting analgesic in the rabbit.",

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AU - Wood, S.

AU - Westt, C. D.

PY - 1988/7/1

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AB - A low cost infrared skin heating system has been designed to measure the efficacy of analgesics in rabbits. Following construction of a prototype, it was used to assess the effect of buprenorphine given subcutaneously and per rectum. Buprenorphine administered subcutaneously has a rapid onset of action, but its duration (8-10 h) appears slightly shorter than has been suggested previously; rectal administration appears to prolong its effect. Preliminary data show that lofentanil has a longer duration of action than buprenorphine and it may prove, therefore, to be a valuable long-acting analgesic in the rabbit.

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An analgesiometry system for use in rabbits with some preliminary data on the effects of buprenorphine and lofentanil

Abstract

Keywords

ASJC Scopus subject areas

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