Alternative hydrogen source for asymmetric transfer hydrogenation in the reduction of ketones

Russell J. Wakeham, James A. Morris, Jonathan M. J. Williams

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

cis-1,4-Butenediol is shown to be a highly active hydrogen source for asymmetric transfer hydrogenation in the reduction of ketones. With the use of a ruthenium catalyst, cis-1,4-butenediol is isomerised and subsequently oxidised to a lactone as an irreversible step, which provides the driving force for the asymmetric reduction of ketones.

Original languageEnglish
Pages (from-to)4039-4041
JournalChemCatChem
Volume7
Issue number24
Early online date23 Oct 2015
DOIs
Publication statusPublished - 14 Dec 2015

Keywords

  • Hydrogen
  • Hydrogenation
  • Ketones
  • Reduction
  • Ruthenium

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  • Projects

    Dream Fellowship

    Williams, J.

    Engineering and Physical Sciences Research Council

    1/08/1110/05/13

    Project: Research council

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