Abstract

During adolescence and puberty, alterations in pain, both experimental and clinical, are observed. In addition, adolescents undergo extensive biopsychosocial changes as they transition from childhood to adulthood. However, a better understanding of how the biopsychosocial changes during adolescence impact pain is needed to improve pain management and develop targeted pain interventions for adolescents. This review synthesizes the literature on alterations in pain during adolescence in humans, describes the potential biopsychosocial factors impacting pain during adolescence, and suggests future research directions to advance the understanding of the impact of adolescent development on pain.
Original languageEnglish
Pages (from-to)307-317
Number of pages11
JournalTrends in Neurosciences
Volume46
Issue number4
Early online date24 Feb 2023
DOIs
Publication statusPublished - 30 Apr 2023

Funding

K.E.B. is supported by a postdoctoral fellowship from the Canadian Child Health Clinician Scientist Program . R.L. is supported by the Center for Child Health, Behavior and Development (CCHBD) Hearst Foundation Fellowship Award at Seattle Children’s Research Institute.

FundersFunder number
Hearst Foundations
Center for Child Health, Behavior and Development
Canadian Child Health Clinician Scientist Program

    Keywords

    • biopsychosocial
    • brain
    • development
    • hormones
    • nociception
    • sex

    ASJC Scopus subject areas

    • General Neuroscience

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