AFM nanotools for surgery of biological Cells

James D Beard, Sergey N Gordeev, Richard H Guy

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Abstract

Using a method of electron-beam induced deposition, we have been able to fabricate specialized AFM probes with application as "nanotools" for the manipulation of biological structures ("nanosurgery"). We describe several such tools, including a "nanoscalpel", " nanoneedles" for probing intracellular structures, and a "nanotome" which can separate surface layers from a biological structure. These applications are demonstrated by performing nanomanipulation on corneocyte cells from the outer layer of human skin.
Original languageEnglish
Article number012003
JournalJournal of Physics: Conference Series
Volume286
Issue number1
DOIs
Publication statusPublished - 2011
Event1st Condensed Matter and Materials Physics Conference, CMMP10 - Warwick, UK United Kingdom
Duration: 14 Dec 201016 Dec 2010

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