Using a method of electron-beam induced deposition, we have been able to fabricate specialized AFM probes with application as "nanotools" for the manipulation of biological structures ("nanosurgery"). We describe several such tools, including a "nanoscalpel", " nanoneedles" for probing intracellular structures, and a "nanotome" which can separate surface layers from a biological structure. These applications are demonstrated by performing nanomanipulation on corneocyte cells from the outer layer of human skin.
|Journal||Journal of Physics: Conference Series|
|Publication status||Published - 2011|
|Event||1st Condensed Matter and Materials Physics Conference, CMMP10 - Warwick, UK United Kingdom|
Duration: 14 Dec 2010 → 16 Dec 2010