Acute Exercise as an Adjuvant to Influenza Vaccination

Kate M. Edwards, John P. Campbell

Research output: Contribution to journalArticlepeer-review

10 Citations (SciVal)


Acute exercise prior to vaccine administration can improve the immune response. Animal data are now supported by human trials, which have shown that immune responses are enhanced by a bout of acute exercise before innoculation; this effect is particularly prominent in vaccines that normally produce weak immune responses. Although there remain many aspects of this phenomenon to be investigated, including task characteristics such as duration and form of exercise, it appears that even a moderate bout of exercise of the muscles into which vaccine will be administered can enhance the antibody response. In this review, the authors will summarize the animal and human literature and discuss the investigation of potential mechanisms of acute exerciseã¢â‚¬â€œinduced immunoenhancement.

Original languageEnglish
Pages (from-to)512-517
Number of pages6
JournalAmerican Journal of Lifestyle Medicine
Issue number6
Publication statusPublished - 1 Jan 2011


  • acute exercise
  • antibody
  • behavioral adjuvant
  • influenza
  • vaccination

ASJC Scopus subject areas

  • Medicine (miscellaneous)
  • Health Policy
  • Public Health, Environmental and Occupational Health


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