TY - JOUR
T1 - Accelerating innovations in C[sbnd]H activation/functionalization through intricately designed magnetic nanomaterials
T2 - From genesis to applicability in liquid/regio/photo catalysis
AU - Dutta, Sriparna
AU - Kumar, Prashant
AU - Yadav, Sneha
AU - Sharma, Ruchi Dubey
AU - Shivaprasad, Parimala
AU - Vimaleswaran, Karani S.
AU - Srivastava, Anju
AU - Sharma, Rakesh K.
N1 - Funding Information:
The authors would like to thank British Council for providing grant for INDO-UK Collaborative workshop and this research output is an outcome of the same. One of the authors would also like to express gratitude to SERB for providing fund to Dr. Prashant Kumar under the scheme of Teacher Associateship for Research Excellence (TARE) (File number TAR/2021/000201).
Data availability
Data will be made available on request.
PY - 2023/2/28
Y1 - 2023/2/28
N2 - Selective functionalization of highly inert and ubiquitous C[sbnd]H bonds that would provide a ready access to synthetically valuable motifs has perplexed the chemists since long. Also, environmental benignity and economic viability have been the prime factors driving tremendous interest in C[sbnd]H functionalization. This has led to many inspiring discoveries infuriating the development of potent catalytic systems that enable the facile replacement of the C[sbnd]H bonds with conventional functional groups, allowing the construction of C-C, C-N, C-O, C-S, C-B and C-halogen bonds at both sp2 as well as sp3 centres. In fact, catalytic C[sbnd]H functionalization strategies integrating the benefits of magnetic recovery have emerged as sustainable gateway for affording a diverse array of transformations. This review sheds light on the remarkable advancements witnessed in this area as a consequence of integrating the inherent magnetism of catalysts with the cutting-edge direct C[sbnd]H functionalization strategy. Also, the promising future perspectives comprehensively covered in this review is anticipated to motivate the academic and industrial researchers, arousing their creativity for designing competent sustainable strategies to generate a plethora of pharmaceutically active molecules.
AB - Selective functionalization of highly inert and ubiquitous C[sbnd]H bonds that would provide a ready access to synthetically valuable motifs has perplexed the chemists since long. Also, environmental benignity and economic viability have been the prime factors driving tremendous interest in C[sbnd]H functionalization. This has led to many inspiring discoveries infuriating the development of potent catalytic systems that enable the facile replacement of the C[sbnd]H bonds with conventional functional groups, allowing the construction of C-C, C-N, C-O, C-S, C-B and C-halogen bonds at both sp2 as well as sp3 centres. In fact, catalytic C[sbnd]H functionalization strategies integrating the benefits of magnetic recovery have emerged as sustainable gateway for affording a diverse array of transformations. This review sheds light on the remarkable advancements witnessed in this area as a consequence of integrating the inherent magnetism of catalysts with the cutting-edge direct C[sbnd]H functionalization strategy. Also, the promising future perspectives comprehensively covered in this review is anticipated to motivate the academic and industrial researchers, arousing their creativity for designing competent sustainable strategies to generate a plethora of pharmaceutically active molecules.
KW - C[sbnd]H functionalization
KW - Heterocycles
KW - Magnetic nanocatalysts
KW - Magnetic retrievability
KW - Sustainable synthesis
UR - http://www.scopus.com/inward/record.url?scp=85147275975&partnerID=8YFLogxK
U2 - 10.1016/j.catcom.2023.106615
DO - 10.1016/j.catcom.2023.106615
M3 - Review article
AN - SCOPUS:85147275975
VL - 175
JO - Catalysis Communications
JF - Catalysis Communications
SN - 1566-7367
M1 - 106615
ER -