A compact and versatile continuous reaction system for supercritical fluids as mobile phase was realised using commercially available components where possible. All process parameters of particular importance to the specific properties of near- or supercritical fluids such as pressure, temperature, and composition (p, T, x) can be accurately controlled over a wide flow range. The setup is completely automated by the help of computerised control and features a view cell for inline phase behavior observation. Coupling to supercritical fluid chromatography permits sampling under process conditions for reaction monitoring. Potential applications include continuous flow synthesis and catalysis, extractions, and other operations demanding controlled application of compressible gases. Highly efficient continuous flow asymmetric hydrogenation catalysis with integrated product separation is demonstrated.