A stereochemical investigation of the cyclisation of D-glucose-6[(R)-16O,17O,18O]phosphate and adenosine-5′[(R)-16O,17O,18O]phosphate

Richard L. Jarvest, Gordon Lowe, Barry V. L. Potter

Research output: Contribution to journalArticlepeer-review

Abstract

D-Glucose-6[(R)-16O,17O,18O] phosphate and adenosine-5′[(R)-16O,17O,18O] phosphate were synthesised and converted (by treatment with diphenyl phosphorochloridate, followed by potassium t-butoxide) into the cyclic 4,6-phosphate and 3′5′-phosphate diesters respectively with retention of configuration at phosphorus; the absolute configuration of D-glucose-6[16O,17O,18O]phosphate and adenosine-5′[16O,17O,18O]phosphate of unknown chirality at phosphorus can now be determined by 31P n.m.r. spectroscopy

Original languageEnglish
Pages (from-to)1142-1145
JournalJournal of the Chemical Society, Chemical Communications
Volume1980
Issue number23
DOIs
Publication statusPublished - 1980

Fingerprint

Dive into the research topics of 'A stereochemical investigation of the cyclisation of D-glucose-6[(R)-16O,17O,18O]phosphate and adenosine-5′[(R)-16O,17O,18O]phosphate'. Together they form a unique fingerprint.

Cite this