A stable methyl phosphane oxide/lithium amide complex: A structural and MO calculational investigation of the mechanism of proton abstraction by alkali metal reagents

David R. Armstrong; Matthew G. Davidson; Robert P. Davies; Helen J. Mitchell; Rachel M. Oakley; Paul R. Raithby; Ronald Snaith; Stuart Warren

doi:10.1002/anie.199619421

A stable methyl phosphane oxide/lithium amide complex: A structural and MO calculational investigation of the mechanism of proton abstraction by alkali metal reagents

David R. Armstrong, Matthew G. Davidson, Robert P. Davies, Helen J. Mitchell, Rachel M. Oakley, Paul R. Raithby, Ronald Snaith, Stuart Warren

Research output: Contribution to journal › Article › peer-review

29 Citations (SciVal)

Abstract

The initiation step in a deprotonation of CH-acidic compounds could be the formation of a complex between the organic precursor and the metalation reagent. This is the conclusion drawn from the reaction of Ph2P(O)CH3 with (Me3Si)2NLi, which yielded a stable dimeric adduct [(Me3Si)2NLi·OP(CH3)Ph2]2 with a central Li2N2 ring. MO calculations on the model system H2LiNLi·OP(CH3)2 support these experimental findings.

Original language	English
Pages (from-to)	1942-1944
Number of pages	3
Journal	Angewandte Chemie (International Edition in English)
Volume	35
Issue number	17
DOIs	https://doi.org/10.1002/anie.199619421
Publication status	Published - 20 Sept 1996

Keywords

ab initio calculations
Amides
Lithium compounds
Phosphorus compounds
Solid-state structures

ASJC Scopus subject areas

Catalysis
General Chemistry

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10.1002/anie.199619421

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Armstrong, D. R., Davidson, M. G., Davies, R. P., Mitchell, H. J., Oakley, R. M., Raithby, P. R., Snaith, R., & Warren, S. (1996). A stable methyl phosphane oxide/lithium amide complex: A structural and MO calculational investigation of the mechanism of proton abstraction by alkali metal reagents. Angewandte Chemie (International Edition in English), 35(17), 1942-1944. https://doi.org/10.1002/anie.199619421

A stable methyl phosphane oxide/lithium amide complex: A structural and MO calculational investigation of the mechanism of proton abstraction by alkali metal reagents. / Armstrong, David R.; Davidson, Matthew G.; Davies, Robert P. et al.
In: Angewandte Chemie (International Edition in English), Vol. 35, No. 17, 20.09.1996, p. 1942-1944.

Research output: Contribution to journal › Article › peer-review

Armstrong, DR, Davidson, MG, Davies, RP, Mitchell, HJ, Oakley, RM, Raithby, PR, Snaith, R & Warren, S 1996, 'A stable methyl phosphane oxide/lithium amide complex: A structural and MO calculational investigation of the mechanism of proton abstraction by alkali metal reagents', Angewandte Chemie (International Edition in English), vol. 35, no. 17, pp. 1942-1944. https://doi.org/10.1002/anie.199619421

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AU - Warren, Stuart

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A stable methyl phosphane oxide/lithium amide complex: A structural and MO calculational investigation of the mechanism of proton abstraction by alkali metal reagents

Abstract

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