A Simple Near-Infrared Fluorescent Probe for the Detection of Peroxynitrite

Luling Wu, Xue Tian, Hai Hao Han, Jie Wang, Robin R. Groleau, Paramabhorn Tosuwan, Boontana Wannalerse, Adam C. Sedgwick, Steven D. Bull, Xiao Peng He, Tony D. James

Research output: Contribution to journalArticle

Abstract

Herein, we report the evaluation and synthesis of a reaction based fluorescent probe DCM-Bpin for the detection of peroxynitrite (ONOO). DCM-Bpin exhibits selective fluorescence off-on response for ONOO over other reactive oxygen species, including H2O2. Moreover, DCM-Bpin is biocompatible and has been used to visualize exogenous ONOO in HeLa cells.

Original languageEnglish
Pages (from-to)1407-1409
Number of pages3
JournalChemistryOpen
Volume8
Issue number12
Early online date9 Dec 2019
DOIs
Publication statusPublished - 9 Dec 2019

Keywords

  • boronate
  • fluorescence
  • near-infrared
  • peroxynitrite
  • probe

ASJC Scopus subject areas

  • Chemistry(all)

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