Abstract

We describe the synthesis and evaluation of an azulene-based chemodosimeter for nitrite. The probe was found to undergo two distinct color changes upon introduction of aqueous nitrite ion. A near-instant formation of a grey color provides a qualitative indication of the presence of nitrite, followed by the formation of a deep-yellow/ orange color, the endpoint from which quantitative data can be derived. The azulene probe exhibits 1:1 stoichiometry of reaction with nitrite in water, and is selective for nitrite over other anions. The azulene probe was applied to determine nitrite content in cured meat, and compared with the British Standard testing procedure (Griess test). The value obtained from the azulene-based probe agreed closely with the standard test. Our procedure only requires the preparation of one standard solution, instead of the three required for the standard Griess test.
LanguageEnglish
Number of pages7
JournalFrontiers of Chemical Science and Engineering
Early online date22 Mar 2019
DOIs
StatusE-pub ahead of print - 22 Mar 2019

Cite this

@article{ff726be40afa46faa8a49d68d2e452f8,
title = "A simple, azulene-based colorimetric probe for the detection of nitrite in water",
abstract = "We describe the synthesis and evaluation of an azulene-based chemodosimeter for nitrite. The probe was found to undergo two distinct color changes upon introduction of aqueous nitrite ion. A near-instant formation of a grey color provides a qualitative indication of the presence of nitrite, followed by the formation of a deep-yellow/ orange color, the endpoint from which quantitative data can be derived. The azulene probe exhibits 1:1 stoichiometry of reaction with nitrite in water, and is selective for nitrite over other anions. The azulene probe was applied to determine nitrite content in cured meat, and compared with the British Standard testing procedure (Griess test). The value obtained from the azulene-based probe agreed closely with the standard test. Our procedure only requires the preparation of one standard solution, instead of the three required for the standard Griess test.",
author = "Lloyd Murfin and Lopez-Alled, {Carlos Miguel} and Simon Lewis and Jannis Wenk and Tony James and Adam Sedgwick",
year = "2019",
month = "3",
day = "22",
doi = "10.1007/s11705-019-1790-7",
language = "English",
journal = "Frontiers of Chemical Science and Engineering",
issn = "2095-0179",
publisher = "Springer Verlag",

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TY - JOUR

T1 - A simple, azulene-based colorimetric probe for the detection of nitrite in water

AU - Murfin, Lloyd

AU - Lopez-Alled, Carlos Miguel

AU - Lewis, Simon

AU - Wenk, Jannis

AU - James, Tony

AU - Sedgwick, Adam

PY - 2019/3/22

Y1 - 2019/3/22

N2 - We describe the synthesis and evaluation of an azulene-based chemodosimeter for nitrite. The probe was found to undergo two distinct color changes upon introduction of aqueous nitrite ion. A near-instant formation of a grey color provides a qualitative indication of the presence of nitrite, followed by the formation of a deep-yellow/ orange color, the endpoint from which quantitative data can be derived. The azulene probe exhibits 1:1 stoichiometry of reaction with nitrite in water, and is selective for nitrite over other anions. The azulene probe was applied to determine nitrite content in cured meat, and compared with the British Standard testing procedure (Griess test). The value obtained from the azulene-based probe agreed closely with the standard test. Our procedure only requires the preparation of one standard solution, instead of the three required for the standard Griess test.

AB - We describe the synthesis and evaluation of an azulene-based chemodosimeter for nitrite. The probe was found to undergo two distinct color changes upon introduction of aqueous nitrite ion. A near-instant formation of a grey color provides a qualitative indication of the presence of nitrite, followed by the formation of a deep-yellow/ orange color, the endpoint from which quantitative data can be derived. The azulene probe exhibits 1:1 stoichiometry of reaction with nitrite in water, and is selective for nitrite over other anions. The azulene probe was applied to determine nitrite content in cured meat, and compared with the British Standard testing procedure (Griess test). The value obtained from the azulene-based probe agreed closely with the standard test. Our procedure only requires the preparation of one standard solution, instead of the three required for the standard Griess test.

U2 - 10.1007/s11705-019-1790-7

DO - 10.1007/s11705-019-1790-7

M3 - Article

JO - Frontiers of Chemical Science and Engineering

T2 - Frontiers of Chemical Science and Engineering

JF - Frontiers of Chemical Science and Engineering

SN - 2095-0179

ER -