Abstract
A procedure allowing access to unprecedented tripeptides containing a trans-2-aminocyclopropanecarboxylic acid residue in their central position has been established. The key features of the strategy are the use of a masked trans-2-aminocyclopropanecarboxylic acid monomer equivalent for C-terminal coupling and full N-Boc protection of all amide groups until the final step.
| Original language | English |
|---|---|
| Pages (from-to) | 100-103 |
| Number of pages | 4 |
| Journal | Organic Letters |
| Volume | 21 |
| Issue number | 1 |
| Early online date | 17 Dec 2018 |
| DOIs | |
| Publication status | Published - 4 Jan 2019 |
ASJC Scopus subject areas
- Biochemistry
- Physical and Theoretical Chemistry
- Organic Chemistry
Cite this
A Selective Deprotection Strategy for the Construction of trans-2-Aminocyclopropanecarboxylic Acid Derived Peptides. / Boddaert, Thomas; Taylor, James E.; Bull, Steven D.; Aitken, David J.
In: Organic Letters, Vol. 21, No. 1, 04.01.2019, p. 100-103.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - A Selective Deprotection Strategy for the Construction of trans-2-Aminocyclopropanecarboxylic Acid Derived Peptides
AU - Boddaert, Thomas
AU - Taylor, James E.
AU - Bull, Steven D.
AU - Aitken, David J.
PY - 2019/1/4
Y1 - 2019/1/4
N2 - A procedure allowing access to unprecedented tripeptides containing a trans-2-aminocyclopropanecarboxylic acid residue in their central position has been established. The key features of the strategy are the use of a masked trans-2-aminocyclopropanecarboxylic acid monomer equivalent for C-terminal coupling and full N-Boc protection of all amide groups until the final step.
AB - A procedure allowing access to unprecedented tripeptides containing a trans-2-aminocyclopropanecarboxylic acid residue in their central position has been established. The key features of the strategy are the use of a masked trans-2-aminocyclopropanecarboxylic acid monomer equivalent for C-terminal coupling and full N-Boc protection of all amide groups until the final step.
UR - http://www.scopus.com/inward/record.url?scp=85059631123&partnerID=8YFLogxK
U2 - 10.1021/acs.orglett.8b03533
DO - 10.1021/acs.orglett.8b03533
M3 - Article
VL - 21
SP - 100
EP - 103
JO - Organic Letters
JF - Organic Letters
SN - 1523-7060
IS - 1
ER -