A practical asymmetric synthesis of homochiral alpha-arylglycines

C Mellin-Morliere, D J Aitken, S D Bull, S G Davies, H P Husson

Research output: Contribution to journalArticlepeer-review

31 Citations (Scopus)

Abstract

Enantioselective reduction of a series of substituted aryl trichloromethyl ketones with the CBS-catecholborane reagent afforded homochiral aryl trichloromethyl carbinols which have been elaborated to give homochiral alpha -arylglycines in high e.e. (C) 2001 Elsevier Science Ltd. All rights reserved.
Original languageEnglish
Pages (from-to)149-155
Number of pages7
JournalTetrahedron: Asymmetry
Volume12
Issue number1
Publication statusPublished - 2001

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