A practical asymmetric synthesis of homochiral alpha-arylglycines

C Mellin-Morliere; D J Aitken; S D Bull; S G Davies; H P Husson

A practical asymmetric synthesis of homochiral alpha-arylglycines

C Mellin-Morliere, D J Aitken, S D Bull, S G Davies, H P Husson

Department of Chemistry

Research output: Contribution to journal › Article › peer-review

34 Citations (SciVal)

Abstract

Enantioselective reduction of a series of substituted aryl trichloromethyl ketones with the CBS-catecholborane reagent afforded homochiral aryl trichloromethyl carbinols which have been elaborated to give homochiral alpha -arylglycines in high e.e. (C) 2001 Elsevier Science Ltd. All rights reserved.

Original language	English
Pages (from-to)	149-155
Number of pages	7
Journal	Tetrahedron: Asymmetry
Volume	12
Issue number	1
Publication status	Published - 2001

Bibliographical note

ID number: ISI:000167494000022

Cite this

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title = "A practical asymmetric synthesis of homochiral alpha-arylglycines",

abstract = "Enantioselective reduction of a series of substituted aryl trichloromethyl ketones with the CBS-catecholborane reagent afforded homochiral aryl trichloromethyl carbinols which have been elaborated to give homochiral alpha -arylglycines in high e.e. (C) 2001 Elsevier Science Ltd. All rights reserved.",

author = "C Mellin-Morliere and Aitken, {D J} and Bull, {S D} and Davies, {S G} and Husson, {H P}",

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year = "2001",

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volume = "12",

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journal = "Tetrahedron: Asymmetry",

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T1 - A practical asymmetric synthesis of homochiral alpha-arylglycines

AU - Mellin-Morliere, C

AU - Aitken, D J

AU - Bull, S D

AU - Davies, S G

AU - Husson, H P

N1 - ID number: ISI:000167494000022

PY - 2001

Y1 - 2001

N2 - Enantioselective reduction of a series of substituted aryl trichloromethyl ketones with the CBS-catecholborane reagent afforded homochiral aryl trichloromethyl carbinols which have been elaborated to give homochiral alpha -arylglycines in high e.e. (C) 2001 Elsevier Science Ltd. All rights reserved.

AB - Enantioselective reduction of a series of substituted aryl trichloromethyl ketones with the CBS-catecholborane reagent afforded homochiral aryl trichloromethyl carbinols which have been elaborated to give homochiral alpha -arylglycines in high e.e. (C) 2001 Elsevier Science Ltd. All rights reserved.

M3 - Article

SN - 0957-4166

VL - 12

SP - 149

EP - 155

JO - Tetrahedron: Asymmetry

JF - Tetrahedron: Asymmetry

IS - 1

ER -

A practical asymmetric synthesis of homochiral alpha-arylglycines

Abstract

Bibliographical note

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