A practical asymmetric synthesis of homochiral alpha-arylglycines

C Mellin-Morliere, D J Aitken, S D Bull, S G Davies, H P Husson

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31 Citations (Scopus)


Enantioselective reduction of a series of substituted aryl trichloromethyl ketones with the CBS-catecholborane reagent afforded homochiral aryl trichloromethyl carbinols which have been elaborated to give homochiral alpha -arylglycines in high e.e. (C) 2001 Elsevier Science Ltd. All rights reserved.
Original languageEnglish
Pages (from-to)149-155
Number of pages7
JournalTetrahedron: Asymmetry
Issue number1
Publication statusPublished - 2001

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    Mellin-Morliere, C., Aitken, D. J., Bull, S. D., Davies, S. G., & Husson, H. P. (2001). A practical asymmetric synthesis of homochiral alpha-arylglycines. Tetrahedron: Asymmetry, 12(1), 149-155.