A novel automatic method for monitoring Tourette motor tics through a wearable device

M Bernabei, Ezio Preatoni, M Mendez, L Piccini, M Porta, G Andreoni

Research output: Contribution to journalArticle

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Abstract

The aim of this study was to propose a novel automatic method for quantifying motor-tics caused by the Tourette Syndrome (TS). In this preliminary report, the feasibility of the monitoring process was tested over a series of standard clinical trials in a population of 12 subjects affected by TS. A wearable instrument with an embedded three-axial accelerometer was used to detect and classify motor tics during standing and walking activities. An algorithm was devised to analyze acceleration data by: eliminating noise; detecting peaks connected to pathological events; and classifying intensity and frequency of motor tics into quantitative scores. These indexes were compared with the video-based ones provided by expert clinicians, which were taken as the gold-standard. Sensitivity, specificity, and accuracy of tic detection were estimated, and an agreement analysis was performed through the least square regression and the Bland-Altman test. The tic recognition algorithm showed sensitivity = 80.8% ± 8.5% (mean ± SD), specificity = 75.8% ± 17.3%, and accuracy = 80.5% ± 12.2%. The agreement study showed that automatic detection tended to overestimate the number of tics occurred. Although, it appeared this may be a systematic error due to the different recognition principles of the wearable and video-based systems. Furthermore, there was substantial concurrency with the gold-standard in estimating the severity indexes. The proposed methodology gave promising performances in terms of automatic motor-tics detection and classification in a standard clinical context. The system may provide physicians with a quantitative aid for TS assessment. Further developments will focus on the extension of its application to everyday long-term monitoring out of clinical environments.
LanguageEnglish
Pages1967-1972
Number of pages6
JournalMovement Disorders
Volume25
Issue number12
DOIs
StatusPublished - Sep 2010

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Tics
Equipment and Supplies
Tourette Syndrome
Gold
Least-Squares Analysis
Walking
Noise
Clinical Trials
Physicians
Sensitivity and Specificity
Population

Cite this

Bernabei, M., Preatoni, E., Mendez, M., Piccini, L., Porta, M., & Andreoni, G. (2010). A novel automatic method for monitoring Tourette motor tics through a wearable device. DOI: 10.1002/mds.23188

A novel automatic method for monitoring Tourette motor tics through a wearable device. / Bernabei, M; Preatoni, Ezio; Mendez, M; Piccini, L; Porta, M; Andreoni, G.

In: Movement Disorders, Vol. 25, No. 12, 09.2010, p. 1967-1972.

Research output: Contribution to journalArticle

Bernabei, M, Preatoni, E, Mendez, M, Piccini, L, Porta, M & Andreoni, G 2010, 'A novel automatic method for monitoring Tourette motor tics through a wearable device' Movement Disorders, vol. 25, no. 12, pp. 1967-1972. DOI: 10.1002/mds.23188
Bernabei M, Preatoni E, Mendez M, Piccini L, Porta M, Andreoni G. A novel automatic method for monitoring Tourette motor tics through a wearable device. Movement Disorders. 2010 Sep;25(12):1967-1972. Available from, DOI: 10.1002/mds.23188
Bernabei, M ; Preatoni, Ezio ; Mendez, M ; Piccini, L ; Porta, M ; Andreoni, G. / A novel automatic method for monitoring Tourette motor tics through a wearable device. In: Movement Disorders. 2010 ; Vol. 25, No. 12. pp. 1967-1972
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