A new synthesis and preliminary evaluation of some analogues of mecamylamine-a compound with anti-addiction properties

David Mangan, Neasa McNabola, Emily H. Clark, Isabel Bermudez, Susan Wonnacott, J. Mike Southern

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

A new synthesis of mecamylamine-a known anti-hypertensive drug with anti-addictive properties is described. The new route allowed access to two novel analogues whose activity at two nicotinic acetylcholine receptor subtypes was assessed.

Original languageEnglish
Pages (from-to)10787-10798
Number of pages12
JournalOrganic and Biomolecular Chemistry
Volume14
Issue number46
DOIs
Publication statusPublished - 14 Dec 2016

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