A nematode symbiont sheds light on invertebrate immunity

R H Ffrench-Constant; I Eleftherianos; S E Reynolds

doi:10.1016/j.pt.2007.08.021

A nematode symbiont sheds light on invertebrate immunity

R H Ffrench-Constant, I Eleftherianos, S E Reynolds

Department of Life Sciences

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25 Citations (SciVal)

Abstract

Photorhabdus bacteria live in a 'symbiosis of pathogens' with nematodes that invade and kill insects. Recent work has begun to use the power of the model insect Drosophila to dissect the molecular basis of the invertebrate immune response to the combined insult of the worms and their symbiotic bacterial pathogens. By using RNA interference, it is now also possible to dissect this complex tripartite interaction in a range of both model and non-model hosts.

Original language	English
Pages (from-to)	514-517
Number of pages	4
Journal	Trends in Parasitology
Volume	23
Issue number	11
DOIs	https://doi.org/10.1016/j.pt.2007.08.021
Publication status	Published - 2007

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ID number: ISI:000251332400002

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abstract = "Photorhabdus bacteria live in a 'symbiosis of pathogens' with nematodes that invade and kill insects. Recent work has begun to use the power of the model insect Drosophila to dissect the molecular basis of the invertebrate immune response to the combined insult of the worms and their symbiotic bacterial pathogens. By using RNA interference, it is now also possible to dissect this complex tripartite interaction in a range of both model and non-model hosts.",

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AU - Eleftherianos, I

AU - Reynolds, S E

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AB - Photorhabdus bacteria live in a 'symbiosis of pathogens' with nematodes that invade and kill insects. Recent work has begun to use the power of the model insect Drosophila to dissect the molecular basis of the invertebrate immune response to the combined insult of the worms and their symbiotic bacterial pathogens. By using RNA interference, it is now also possible to dissect this complex tripartite interaction in a range of both model and non-model hosts.

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U2 - 10.1016/j.pt.2007.08.021

DO - 10.1016/j.pt.2007.08.021

M3 - Article

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EP - 517

JO - Trends in Parasitology

JF - Trends in Parasitology

IS - 11

ER -

A nematode symbiont sheds light on invertebrate immunity

Abstract

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