A near-infrared colorimetric fluorescent chemodosimeter for the detection of glutathione in living cells

Meng Li, Xumeng Wu, Yao Wang, Yongsheng Li, Weihong Zhu, Tony D. James

Research output: Contribution to journalArticle

157 Citations (Scopus)

Abstract

A novel near-infrared (NIR) and colorimetric fluorescent molecular probe based on a dicyanomethylene-4H-pyran chromophore for the selective detection of glutathione in living cells has been developed. The fluorescence OFF–ON switch is triggered by cleavage of the 2,4-dinitrobenzensulfonyl (DNBS) unit by the interaction with GSH.
Original languageEnglish
Pages (from-to)1751-1753
Number of pages3
JournalChemical Communications
Volume50
Issue number14
Early online date4 Dec 2013
DOIs
Publication statusPublished - 1 Jan 2014

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