A near-infrared colorimetric fluorescent chemodosimeter for the detection of glutathione in living cells

Meng Li; Xumeng Wu; Yao Wang; Yongsheng Li; Weihong Zhu; Tony D. James

doi:10.1039/c3cc48128j

A near-infrared colorimetric fluorescent chemodosimeter for the detection of glutathione in living cells

Meng Li, Xumeng Wu, Yao Wang, Yongsheng Li, Weihong Zhu, Tony D. James

East China University of Science and Technology

Research output: Contribution to journal › Article › peer-review

203 Citations (SciVal)

Abstract

A novel near-infrared (NIR) and colorimetric fluorescent molecular probe based on a dicyanomethylene-4H-pyran chromophore for the selective detection of glutathione in living cells has been developed. The fluorescence OFF–ON switch is triggered by cleavage of the 2,4-dinitrobenzensulfonyl (DNBS) unit by the interaction with GSH.

Original language	English
Pages (from-to)	1751-1753
Number of pages	3
Journal	Chemical Communications
Volume	50
Issue number	14
Early online date	4 Dec 2013
DOIs	https://doi.org/10.1039/c3cc48128j
Publication status	Published - 1 Jan 2014

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abstract = "A novel near-infrared (NIR) and colorimetric fluorescent molecular probe based on a dicyanomethylene-4H-pyran chromophore for the selective detection of glutathione in living cells has been developed. The fluorescence OFF–ON switch is triggered by cleavage of the 2,4-dinitrobenzensulfonyl (DNBS) unit by the interaction with GSH.",

author = "Meng Li and Xumeng Wu and Yao Wang and Yongsheng Li and Weihong Zhu and James, {Tony D.}",

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AU - Wu, Xumeng

AU - Wang, Yao

AU - Li, Yongsheng

AU - Zhu, Weihong

AU - James, Tony D.

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AB - A novel near-infrared (NIR) and colorimetric fluorescent molecular probe based on a dicyanomethylene-4H-pyran chromophore for the selective detection of glutathione in living cells has been developed. The fluorescence OFF–ON switch is triggered by cleavage of the 2,4-dinitrobenzensulfonyl (DNBS) unit by the interaction with GSH.

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UR - http://dx.doi.org/10.1039/c3cc48128j

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A near-infrared colorimetric fluorescent chemodosimeter for the detection of glutathione in living cells

Abstract

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