A model of host response to a multi-stage pathogen

Edgar Delgado-Eckert, Michael Shapiro

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

We model the immune surveillance of a pathogen which passes through n immunologically distinct stages. The biological parameters of this system induce a partial order on the stages, and this, in turn, determines which stages will be subject to immune regulation. This corresponds to the system’s unique asymptotically stable fixed point.
Original languageEnglish
Pages (from-to)201-227
Number of pages27
JournalJournal of Mathematical Biology
Volume63
Issue number2
Early online date2 Oct 2010
Publication statusPublished - Aug 2011

Keywords

  • Models of microepidemics
  • multi-stage pathogen
  • host-pathogen interaction
  • mathmatical models in immunology

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