Abstract
We model the immune surveillance of a pathogen which passes through n immunologically distinct stages. The biological parameters of this system induce a partial order on the stages, and this, in turn, determines which stages will be subject to immune regulation. This corresponds to the system’s unique asymptotically stable fixed point.
| Original language | English |
|---|---|
| Pages (from-to) | 201-227 |
| Number of pages | 27 |
| Journal | Journal of Mathematical Biology |
| Volume | 63 |
| Issue number | 2 |
| Early online date | 2 Oct 2010 |
| Publication status | Published - Aug 2011 |
Keywords
- Models of microepidemics
- multi-stage pathogen
- host-pathogen interaction
- mathmatical models in immunology