A mild Boc deprotection and the importance of a free carboxylate

Ali Thaqi, Adam McCluskey, Janet L. Scott

Research output: Contribution to journalArticle

21 Citations (Scopus)

Abstract

We report a facile and rapid removal of Boc protecting groups using microwave heating in H2O, with deprotection only requiring a free carboxylic acid group in the starting material. Unlike previous approaches, no additional reagents are required.
Original languageEnglish
Pages (from-to)6962-6964
JournalTetrahedron Letters
Volume49
Issue number49
DOIs
Publication statusPublished - 1 Dec 2008

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