A highly oriented cubic phase formed by lipids under shear

Annela M Seddon, Gudrun Lotze, Tomás S Plivelic, Adam M Squires

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31 Citations (SciVal)


We demonstrate the formation of a macroscopically oriented inverse bicontinuous cubic (QII) lipid phase from a sponge (L3) phase by controlled hydration during shear flow. The L3 phase was the monoolein/butanediol/water system; the addition of water reduces the butanediol concentration, inducing the formation of a diamond (QIID) cubic phase, which is oriented by the shear flow. The phenomenon was reproduced in both capillary and Couette geometries, indicating that this represents a robust general route for the production of highly aligned bulk QII samples, with applications in nanomaterial templating and protein research.
Original languageEnglish
Pages (from-to)13860-13863
Number of pages4
JournalJournal of the American Chemical Society
Issue number35
Publication statusPublished - 7 Sept 2011


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