A high-density YAC contig map of human chromosome 22

J E Collins, C G Cole, L J Smink, C L Garrett, M A Leversha, C A Soderlund, G L Maslen, L A Everett, K M Rice, A J Coffey, S G Gregory, R Gwilliam, A Dunham, A F Davies, S Hassock, Christopher Todd, H Lehrach, T J M Hulsebos, J Weissenbach, B Morrow & 12 others R S Kucherlapati, R Wadey, P Scambler, U-J Kim, M I Simon, M Peyard, Y-G Xie, N P Carter, R Durbin, J P Dumanski, D R Bentley, I Dunham

Research output: Contribution to journalArticle

Abstract

We have constructed a high-resolution clone map of human chromosome 22 which integrates the available physical and genetic information, establishing a single consensus. The map consists of all classes of DNA landmarks ordered on 705 yeast artificial chromosomes (YACs) at an average landmark density of more than one per 70 kilobases. This map represents the practical limits of currently available YAC resources and provides the basis for determination of the entire gene content and genomic DNA sequence of human chromosome 22.

Original languageEnglish
Pages (from-to)367-79
Number of pages13
JournalNature
Volume377
Issue number6547 Suppl
DOIs
Publication statusPublished - 28 Sep 1995

Fingerprint

Yeast Artificial Chromosomes
Chromosomes, Human, Pair 22
Human Chromosomes
Clone Cells
DNA
Genes

Keywords

  • Chromosome Mapping
  • Chromosomes, Artificial, Yeast
  • Chromosomes, Human, Pair 22
  • Genetic Markers
  • Humans
  • Sequence Tagged Sites

Cite this

Collins, J. E., Cole, C. G., Smink, L. J., Garrett, C. L., Leversha, M. A., Soderlund, C. A., ... Dunham, I. (1995). A high-density YAC contig map of human chromosome 22. Nature, 377(6547 Suppl), 367-79. https://doi.org/10.1038/377367a0

A high-density YAC contig map of human chromosome 22. / Collins, J E; Cole, C G; Smink, L J; Garrett, C L; Leversha, M A; Soderlund, C A; Maslen, G L; Everett, L A; Rice, K M; Coffey, A J; G Gregory, S; Gwilliam, R; Dunham, A; Davies, A F; Hassock, S; Todd, Christopher; Lehrach, H; Hulsebos, T J M; Weissenbach, J; Morrow, B; Kucherlapati, R S; Wadey, R; Scambler, P; Kim, U-J; Simon, M I; Peyard, M; Xie, Y-G; Carter, N P; Durbin, R; Dumanski, J P; Bentley, D R; Dunham, I.

In: Nature, Vol. 377, No. 6547 Suppl, 28.09.1995, p. 367-79.

Research output: Contribution to journalArticle

Collins, JE, Cole, CG, Smink, LJ, Garrett, CL, Leversha, MA, Soderlund, CA, Maslen, GL, Everett, LA, Rice, KM, Coffey, AJ, G Gregory, S, Gwilliam, R, Dunham, A, Davies, AF, Hassock, S, Todd, C, Lehrach, H, Hulsebos, TJM, Weissenbach, J, Morrow, B, Kucherlapati, RS, Wadey, R, Scambler, P, Kim, U-J, Simon, MI, Peyard, M, Xie, Y-G, Carter, NP, Durbin, R, Dumanski, JP, Bentley, DR & Dunham, I 1995, 'A high-density YAC contig map of human chromosome 22', Nature, vol. 377, no. 6547 Suppl, pp. 367-79. https://doi.org/10.1038/377367a0
Collins JE, Cole CG, Smink LJ, Garrett CL, Leversha MA, Soderlund CA et al. A high-density YAC contig map of human chromosome 22. Nature. 1995 Sep 28;377(6547 Suppl):367-79. https://doi.org/10.1038/377367a0
Collins, J E ; Cole, C G ; Smink, L J ; Garrett, C L ; Leversha, M A ; Soderlund, C A ; Maslen, G L ; Everett, L A ; Rice, K M ; Coffey, A J ; G Gregory, S ; Gwilliam, R ; Dunham, A ; Davies, A F ; Hassock, S ; Todd, Christopher ; Lehrach, H ; Hulsebos, T J M ; Weissenbach, J ; Morrow, B ; Kucherlapati, R S ; Wadey, R ; Scambler, P ; Kim, U-J ; Simon, M I ; Peyard, M ; Xie, Y-G ; Carter, N P ; Durbin, R ; Dumanski, J P ; Bentley, D R ; Dunham, I. / A high-density YAC contig map of human chromosome 22. In: Nature. 1995 ; Vol. 377, No. 6547 Suppl. pp. 367-79.
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