TY - JOUR
T1 - A hemicyanine-based fluorescent probe for ratiometric detection of ClO- and turn-on detection of viscosity and its imaging application in mitochondria of living cells and zebrafish
AU - James, Tony
N1 - We acknowledge the Joint Program for Fostering Talents of National Natural Science Foundation of China and Henan Province (U1304202), State Scholarship Fund (CSC 201908410366), Henan Province Science and Technology Project (222300420523) (212102210646) and The Scientific Research Innovation Team of Xuchang University (2022CXTD001) for financial support. T. D. J. wishes to thank the Royal Society for a Wolfson Research Merit Award and the Open Research Fund of the School of Chemistry and Chemical Engineering, Henan Normal University for support (2020ZD01).
Data availability
All data is supplied in the Supplementary Information
PY - 2023/2/13
Y1 - 2023/2/13
N2 - A water-soluble fluorescent probe 1 based on chromene-hemicyanine has been developed, that exhibits ratiometric fluorescent response toward hypochlorite (ClO-) with the LOD (0.082 μM), and “turn-on” response to viscosity changes. Due to low cytotoxicity and good biocompatibility, probe 1 used to monitor hypochlorous acid and viscosity in mitochondria of living cells and zebrafish.
AB - A water-soluble fluorescent probe 1 based on chromene-hemicyanine has been developed, that exhibits ratiometric fluorescent response toward hypochlorite (ClO-) with the LOD (0.082 μM), and “turn-on” response to viscosity changes. Due to low cytotoxicity and good biocompatibility, probe 1 used to monitor hypochlorous acid and viscosity in mitochondria of living cells and zebrafish.
KW - Fluorescent probe
KW - Hypochlorite
KW - Imaging
KW - Mitochondria targeting
KW - Viscosity
UR - http://www.scopus.com/inward/record.url?scp=85149332749&partnerID=8YFLogxK
U2 - 10.1016/j.snb.2023.133510
DO - 10.1016/j.snb.2023.133510
M3 - Article
VL - 383
JO - Sensors and Actuators B: Chemical
JF - Sensors and Actuators B: Chemical
SN - 0925-4005
M1 - 133510
ER -