A General Method for Motion Compensation in X-ray Computed Tomography

Ander Biguri, Manjit Dosanjh, Steven Hancock, Manuchehr Soleimani

Research output: Contribution to journalArticlepeer-review

9 Citations (SciVal)


Motion during data acquisition is a known source of error in medical tomography, resulting in blur artefacts in the regions that move. It is critical to reduce these artefacts in applications such as image-guided radiation therapy as a clearer image translates into a more accurate treatment and the sparing of healthy tissue close to a tumour site. Most research in 4D x-ray tomography involving the thorax relies on respiratory phase binning of the acquired data and reconstructing each of a set of images using the limited subset of data per phase. In this work, we demonstrate a motion-compensation method to reconstruct images from the complete dataset taken during breathing without recourse to phase-binning or breath-hold techniques. As long as the motion is sufficiently well known, the new method can accurately reconstruct an image at any time during the acquisition time span. It can be applied to any iterative reconstruction algorithm.

Original languageEnglish
Pages (from-to)6532–6549
Number of pages18
JournalPhysics in Medicine and Biology
Issue number16
Early online date24 Jul 2017
Publication statusPublished - 21 Aug 2017


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