A fluorogenic probe for tracking GSH flux in developing neurons

Haichao Zong; Jiayi Peng; Xiao Rong Li; Meng Liu; Yongzhou Hu; Jia Li; Yi Zang; Xin Li; Tony D. James

doi:10.1039/c9cc07753g

A fluorogenic probe for tracking GSH flux in developing neurons

Haichao Zong, Jiayi Peng, Xiao Rong Li, Meng Liu, Yongzhou Hu, Jia Li, Yi Zang, Xin Li, Tony D. James

Chinese Academy of Sciences

Research output: Contribution to journal › Article › peer-review

22 Citations (SciVal)

Abstract

Understanding GSH flux in developing neurons is prerequisite to reveal its role in neuronal development but necessiates an ultrasensitive assay. By systematically exploring key structural factors determing probe sensitivity in live cells, we developed a fluorogenic probe capable of imaging subtle GSH fluctuations in developing neurons.

Original language	English
Pages (from-to)	515-518
Number of pages	4
Journal	Chemical communications (Cambridge, England)
Volume	56
Issue number	4
Early online date	27 Nov 2019
DOIs	https://doi.org/10.1039/c9cc07753g
Publication status	Published - 7 Jan 2020

ASJC Scopus subject areas

Catalysis
Electronic, Optical and Magnetic Materials
Ceramics and Composites
General Chemistry
Surfaces, Coatings and Films
Metals and Alloys
Materials Chemistry

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10.1039/c9cc07753gLicence: CC BY

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title = "A fluorogenic probe for tracking GSH flux in developing neurons",

abstract = "Understanding GSH flux in developing neurons is prerequisite to reveal its role in neuronal development but necessiates an ultrasensitive assay. By systematically exploring key structural factors determing probe sensitivity in live cells, we developed a fluorogenic probe capable of imaging subtle GSH fluctuations in developing neurons.",

author = "Haichao Zong and Jiayi Peng and Li, {Xiao Rong} and Meng Liu and Yongzhou Hu and Jia Li and Yi Zang and Xin Li and James, {Tony D.}",

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AU - Zong, Haichao

AU - Peng, Jiayi

AU - Li, Xiao Rong

AU - Liu, Meng

AU - Hu, Yongzhou

AU - Li, Jia

AU - Zang, Yi

AU - Li, Xin

AU - James, Tony D.

PY - 2020/1/7

Y1 - 2020/1/7

N2 - Understanding GSH flux in developing neurons is prerequisite to reveal its role in neuronal development but necessiates an ultrasensitive assay. By systematically exploring key structural factors determing probe sensitivity in live cells, we developed a fluorogenic probe capable of imaging subtle GSH fluctuations in developing neurons.

AB - Understanding GSH flux in developing neurons is prerequisite to reveal its role in neuronal development but necessiates an ultrasensitive assay. By systematically exploring key structural factors determing probe sensitivity in live cells, we developed a fluorogenic probe capable of imaging subtle GSH fluctuations in developing neurons.

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U2 - 10.1039/c9cc07753g

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EP - 518

JO - Chemical communications (Cambridge, England)

JF - Chemical communications (Cambridge, England)

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A fluorogenic probe for tracking GSH flux in developing neurons

Abstract

ASJC Scopus subject areas

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