A fluorescent peptidyl substrate for visualizing peptidyl-prolyl cis/trans isomerase activity in live cells

Quan Jiang, Xiao-Rong Li, Cheng-Kun Wang, Juan Cheng, Chao Tan, Tian-Tian Cui, Nan-Nan Lu, Tony D James, Feng Han, Xin Li

Research output: Contribution to journalArticle

3 Citations (Scopus)
28 Downloads (Pure)

Abstract

This communication reports on a fluorescent probe (PPI-P) for imaging active peptidyl-prolyl cis/trans isomerases in live cells. PPI-P is capable of responding to both recombinant and cellular PPIases fluorogenically, and has been shown to specifically image active PPIases in live cells.

Original languageEnglish
Pages (from-to)1857-1860
Number of pages4
JournalChemical communications (Cambridge, England)
Volume54
Issue number15
Early online date23 Jan 2018
DOIs
Publication statusPublished - 21 Feb 2018

ASJC Scopus subject areas

  • Catalysis
  • Electronic, Optical and Magnetic Materials
  • Ceramics and Composites
  • Chemistry(all)
  • Surfaces, Coatings and Films
  • Metals and Alloys
  • Materials Chemistry

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