A fluorescent peptidyl substrate for visualizing peptidyl-prolyl cis/trans isomerase activity in live cells

Quan Jiang, Xiao-Rong Li, Cheng-Kun Wang, Juan Cheng, Chao Tan, Tian-Tian Cui, Nan-Nan Lu, Tony D James, Feng Han, Xin Li

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Abstract

This communication reports on a fluorescent probe (PPI-P) for imaging active peptidyl-prolyl cis/trans isomerases in live cells. PPI-P is capable of responding to both recombinant and cellular PPIases fluorogenically, and has been shown to specifically image active PPIases in live cells.

LanguageEnglish
Pages1857-1860
Number of pages4
JournalChemical communications (Cambridge, England)
Volume54
Issue number15
Early online date23 Jan 2018
DOIs
StatusPublished - 21 Feb 2018

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Peptidylprolyl Isomerase
Imaging techniques
Communication
Substrates
Fluorescent Dyes

Keywords

  • Journal Article

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A fluorescent peptidyl substrate for visualizing peptidyl-prolyl cis/trans isomerase activity in live cells. / Jiang, Quan; Li, Xiao-Rong; Wang, Cheng-Kun; Cheng, Juan; Tan, Chao; Cui, Tian-Tian; Lu, Nan-Nan; James, Tony D; Han, Feng; Li, Xin.

In: Chemical communications (Cambridge, England), Vol. 54, No. 15, 21.02.2018, p. 1857-1860.

Research output: Contribution to journalArticle

Jiang, Quan ; Li, Xiao-Rong ; Wang, Cheng-Kun ; Cheng, Juan ; Tan, Chao ; Cui, Tian-Tian ; Lu, Nan-Nan ; James, Tony D ; Han, Feng ; Li, Xin. / A fluorescent peptidyl substrate for visualizing peptidyl-prolyl cis/trans isomerase activity in live cells. In: Chemical communications (Cambridge, England). 2018 ; Vol. 54, No. 15. pp. 1857-1860.
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AU - Tan, Chao

AU - Cui, Tian-Tian

AU - Lu, Nan-Nan

AU - James, Tony D

AU - Han, Feng

AU - Li, Xin

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