A far-red fluorescent probe for sensing laccase in fungi and its application in developing an effective biocatalyst for the biosynthesis of antituberculous dicoumarin

Zhenhao Tian; Qingsong Yan; Lei Feng; Sa Deng; Chao Wang; Jingnan Cui; Chunjie Wang; Zhanjun Zhang; Tony D. James; Xiaochi Ma

doi:10.1039/c9cc01579e

A far-red fluorescent probe for sensing laccase in fungi and its application in developing an effective biocatalyst for the biosynthesis of antituberculous dicoumarin

Zhenhao Tian
, Qingsong Yan
, Lei Feng
, Sa Deng
, Chao Wang
, Jingnan Cui
, Chunjie Wang
, Zhanjun Zhang
, Tony D. James
, Xiaochi Ma

Department of Chemistry

Dalian Medical University
Dalian University of Technology
Beijing Normal University
University of Bath

Research output: Contribution to journal › Article › peer-review

16 Citations (SciVal)

Abstract

A far-red fluorescent probe has been developed for sensing fungal laccase. The probe was used to determine that Rhizopus oryzae had a high level endogenous laccase amongst 24 fungal strains. The Rhizopus oryzae was then used as a biocatalyst for the preparation of dicoumarin resulting in significant inhibition of Mycobacterium tuberculosis H37Ra.

Original language	English
Pages (from-to)	3951-3954
Number of pages	4
Journal	Chemical Communications
Volume	55
Issue number	27
Early online date	8 Mar 2019
DOIs	https://doi.org/10.1039/c9cc01579e
Publication status	Published - 7 Apr 2019

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

ASJC Scopus subject areas

Catalysis
Electronic, Optical and Magnetic Materials
Ceramics and Composites
General Chemistry
Surfaces, Coatings and Films
Metals and Alloys
Materials Chemistry

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10.1039/c9cc01579eLicence: CC BY

Cite this

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abstract = "A far-red fluorescent probe has been developed for sensing fungal laccase. The probe was used to determine that Rhizopus oryzae had a high level endogenous laccase amongst 24 fungal strains. The Rhizopus oryzae was then used as a biocatalyst for the preparation of dicoumarin resulting in significant inhibition of Mycobacterium tuberculosis H37Ra.",

author = "Zhenhao Tian and Qingsong Yan and Lei Feng and Sa Deng and Chao Wang and Jingnan Cui and Chunjie Wang and Zhanjun Zhang and James, \{Tony D.\} and Xiaochi Ma",

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T1 - A far-red fluorescent probe for sensing laccase in fungi and its application in developing an effective biocatalyst for the biosynthesis of antituberculous dicoumarin

AU - Tian, Zhenhao

AU - Yan, Qingsong

AU - Feng, Lei

AU - Deng, Sa

AU - Wang, Chao

AU - Cui, Jingnan

AU - Wang, Chunjie

AU - Zhang, Zhanjun

AU - James, Tony D.

AU - Ma, Xiaochi

PY - 2019/4/7

Y1 - 2019/4/7

N2 - A far-red fluorescent probe has been developed for sensing fungal laccase. The probe was used to determine that Rhizopus oryzae had a high level endogenous laccase amongst 24 fungal strains. The Rhizopus oryzae was then used as a biocatalyst for the preparation of dicoumarin resulting in significant inhibition of Mycobacterium tuberculosis H37Ra.

AB - A far-red fluorescent probe has been developed for sensing fungal laccase. The probe was used to determine that Rhizopus oryzae had a high level endogenous laccase amongst 24 fungal strains. The Rhizopus oryzae was then used as a biocatalyst for the preparation of dicoumarin resulting in significant inhibition of Mycobacterium tuberculosis H37Ra.

UR - https://www.scopus.com/pages/publications/85063953916

U2 - 10.1039/c9cc01579e

DO - 10.1039/c9cc01579e

M3 - Article

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AN - SCOPUS:85063953916

SN - 1359-7345

VL - 55

SP - 3951

EP - 3954

JO - Chemical Communications

JF - Chemical Communications

IS - 27

ER -

A far-red fluorescent probe for sensing laccase in fungi and its application in developing an effective biocatalyst for the biosynthesis of antituberculous dicoumarin

Abstract

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ASJC Scopus subject areas

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