A far-red fluorescent probe for sensing laccase in fungi and its application in developing an effective biocatalyst for the biosynthesis of antituberculous dicoumarin

Zhenhao Tian; Qingsong Yan; Lei Feng; Sa Deng; Chao Wang; Jingnan Cui; Chunjie Wang; Zhanjun Zhang; Tony D. James; Xiaochi Ma

doi:10.1039/c9cc01579e

A far-red fluorescent probe for sensing laccase in fungi and its application in developing an effective biocatalyst for the biosynthesis of antituberculous dicoumarin

Zhenhao Tian, Qingsong Yan, Lei Feng, Sa Deng, Chao Wang, Jingnan Cui, Chunjie Wang, Zhanjun Zhang, Tony D. James, Xiaochi Ma

Department of Chemistry

Research output: Contribution to journal › Article › peer-review

11 Citations (SciVal)

Abstract

A far-red fluorescent probe has been developed for sensing fungal laccase. The probe was used to determine that Rhizopus oryzae had a high level endogenous laccase amongst 24 fungal strains. The Rhizopus oryzae was then used as a biocatalyst for the preparation of dicoumarin resulting in significant inhibition of Mycobacterium tuberculosis H37Ra.

Original language	English
Pages (from-to)	3951-3954
Number of pages	4
Journal	Chemical Communications
Volume	55
Issue number	27
Early online date	8 Mar 2019
DOIs	https://doi.org/10.1039/c9cc01579e
Publication status	Published - 7 Apr 2019

ASJC Scopus subject areas

Catalysis
Electronic, Optical and Magnetic Materials
Ceramics and Composites
General Chemistry
Surfaces, Coatings and Films
Metals and Alloys
Materials Chemistry

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1039/c9cc01579eLicence: CC BY

Cite this

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abstract = "A far-red fluorescent probe has been developed for sensing fungal laccase. The probe was used to determine that Rhizopus oryzae had a high level endogenous laccase amongst 24 fungal strains. The Rhizopus oryzae was then used as a biocatalyst for the preparation of dicoumarin resulting in significant inhibition of Mycobacterium tuberculosis H37Ra.",

author = "Zhenhao Tian and Qingsong Yan and Lei Feng and Sa Deng and Chao Wang and Jingnan Cui and Chunjie Wang and Zhanjun Zhang and James, {Tony D.} and Xiaochi Ma",

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T1 - A far-red fluorescent probe for sensing laccase in fungi and its application in developing an effective biocatalyst for the biosynthesis of antituberculous dicoumarin

AU - Tian, Zhenhao

AU - Yan, Qingsong

AU - Feng, Lei

AU - Deng, Sa

AU - Wang, Chao

AU - Cui, Jingnan

AU - Wang, Chunjie

AU - Zhang, Zhanjun

AU - James, Tony D.

AU - Ma, Xiaochi

PY - 2019/4/7

Y1 - 2019/4/7

N2 - A far-red fluorescent probe has been developed for sensing fungal laccase. The probe was used to determine that Rhizopus oryzae had a high level endogenous laccase amongst 24 fungal strains. The Rhizopus oryzae was then used as a biocatalyst for the preparation of dicoumarin resulting in significant inhibition of Mycobacterium tuberculosis H37Ra.

AB - A far-red fluorescent probe has been developed for sensing fungal laccase. The probe was used to determine that Rhizopus oryzae had a high level endogenous laccase amongst 24 fungal strains. The Rhizopus oryzae was then used as a biocatalyst for the preparation of dicoumarin resulting in significant inhibition of Mycobacterium tuberculosis H37Ra.

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U2 - 10.1039/c9cc01579e

DO - 10.1039/c9cc01579e

M3 - Article

C2 - 30874262

AN - SCOPUS:85063953916

SN - 1359-7345

VL - 55

SP - 3951

EP - 3954

JO - Chemical Communications

JF - Chemical Communications

IS - 27

ER -

A far-red fluorescent probe for sensing laccase in fungi and its application in developing an effective biocatalyst for the biosynthesis of antituberculous dicoumarin

Abstract

ASJC Scopus subject areas

UN SDGs

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