A far-red fluorescent probe for sensing laccase in fungi and its application in developing an effective biocatalyst for the biosynthesis of antituberculous dicoumarin

Zhenhao Tian, Qingsong Yan, Lei Feng, Sa Deng, Chao Wang, Jingnan Cui, Chunjie Wang, Zhanjun Zhang, Tony D. James, Xiaochi Ma

Research output: Contribution to journalArticlepeer-review

4 Citations (Scopus)

Abstract

A far-red fluorescent probe has been developed for sensing fungal laccase. The probe was used to determine that Rhizopus oryzae had a high level endogenous laccase amongst 24 fungal strains. The Rhizopus oryzae was then used as a biocatalyst for the preparation of dicoumarin resulting in significant inhibition of Mycobacterium tuberculosis H37Ra.

Original languageEnglish
Pages (from-to)3951-3954
Number of pages4
JournalChemical Communications
Volume55
Issue number27
Early online date8 Mar 2019
DOIs
Publication statusPublished - 7 Apr 2019

ASJC Scopus subject areas

  • Catalysis
  • Electronic, Optical and Magnetic Materials
  • Ceramics and Composites
  • Chemistry(all)
  • Surfaces, Coatings and Films
  • Metals and Alloys
  • Materials Chemistry

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