A direct synthesis of 2-deoxy-2-fluoro-α-D-[6-3H]glucopyranosyl uridine-5′-diphosphate

Robert V. Stick, Andrew G. Watts

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

The synthesis of 2-deoxy-2-fluoro-α-D[6-3H]glucopyranosyl uridine-5′-diphosphate, with the late introduction of the radiolable, has been achieved from 3,4-di-O-benzyl-2-deoxy-2-fluoro-α-D-glucosyl diphenyl phosphate, by an oxidation-reduction sequence, followed by protecting group removal and morpholidate coupling to uridine-5′-monophosphate.

Original languageEnglish
Pages (from-to)327-329
Number of pages3
JournalAustralian Journal of Chemistry
Volume55
Issue number5
DOIs
Publication statusPublished - 2 Aug 2002

ASJC Scopus subject areas

  • Chemistry(all)

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