A convenient synthesis of cyclic peptides as regioselectively addressable functionalized templates (RAFT)

Pascal Dumy, Ian Eggleston, Stefano Cervigni, Ursula Sila, Xicheng Sun, Manfred Mutter

Research output: Contribution to journalArticlepeer-review

Abstract

Cyclic decapeptides containing up to four orthogonally protected lysine residues have been efficiently prepared by a combined solid phase and solution strategy. These cyclic peptides present new Regioselectively Addressable Functionalized Templates (RAFT), which are suitable for use in protein de novo design according to the TASP concept
Original languageEnglish
Pages (from-to)1255
Number of pages1258
JournalTetrahedron Letters
Volume36
Issue number8
DOIs
Publication statusPublished - 1995

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