Find Research Outputs

Search in all content

Filters for Research Output

Search concepts
Selected filters

Publication Year

  • 2020
  • 2019
  • 2018
  • 2017
  • 2016
  • 2015
  • 2014
  • 2013
  • 2012
  • 2011

Author

  • Richard Guy
2019

Mechanism of human nail poration by high-repetition-rate, femtosecond laser ablation

Vanstone, S., Stone, J., Gordeev, S. & Guy, R., 31 Oct 2019, In : Drug Delivery and Translational Research. 9, 5, p. 956–967 12 p.

Research output: Contribution to journalArticle

Open Access

Potential of iontophoresis as a drug delivery method for midazolam in pediatrics

Djabri, A., Guy, R. & Delgado-Charro, M., 1 Feb 2019, In : European Journal of Pharmaceutical Sciences. 128, p. 137-143 7 p.

Research output: Contribution to journalArticle

Open Access
File
2 Citations (Scopus)
29 Downloads (Pure)

Regulatory Science and Innovation Programme for Europe (ReScIPE): A proposed model

Hines, P. A., Guy, R. H., Brand, A., Humphreys, A. J. & Papaluca-Amati, M., 19 Aug 2019, In : British Journal Of Clinical Pharmacology. p. 1-6 6 p.

Research output: Contribution to journalArticle

Open Access
File
2 Citations (Scopus)
21 Downloads (Pure)

Scanning the horizon: a systematic literature review of methodologies

Hines, P., Yu, L. H., Guy, R. & Papaluca-Amati, M., 27 May 2019, BMJ Open, 9, 5, p. e026764 9 p.

Research output: Contribution to specialist publicationArticle

Open Access
1 Citation (Scopus)
Open Access
3 Citations (Scopus)

Stratum corneum sampling to assess bioequivalence between topical acyclovir products

Pensado-Lopez, A., Chiu, W. S., Cordery, S., Rantou, E., Bunge, A. L., Delgado-Charro, B. & Guy, R., 1 Dec 2019, In : Pharmaceutical Research. 36, 12, p. 180-196 16 p., 180.

Research output: Contribution to journalArticle

Open Access

The European Medicines Agency’s goals for regulatory science to 2025

Hines, P., Guy, R., Humphreys, A. & Papaluca-Amati, M., 3 Jun 2019, In : Nature Reviews Drug Discovery. 18, 6, p. 403-404 2 p.

Research output: Contribution to journalComment/debate

Open Access
File
5 Citations (Scopus)
21 Downloads (Pure)
2018

Comparison of patient (POEM), observer (EASI, SASSAD, TIS) and corneometry measures of emollient effectiveness in children with eczema: findings from the COMET feasibility trial

Ridd, M. J., Gaunt, D. M., Guy, R. H., Redmond, N. M., Garfield, K., Hollinghurst, S., Ball, N., Shaw, L., Purdy, S. & Metcalfe, C., 1 Aug 2018, In : British Journal of Dermatology. 179, 2, p. 362-370 9 p.

Research output: Contribution to journalArticle

Open Access
File
2 Citations (Scopus)
38 Downloads (Pure)

Dermal Absorption of Pesticide Residues

Clarke, J., Cordery, S., Morgan, N. A., Knowles, P. & Guy, R., 17 Dec 2018, In : Chemical Research in Toxicology. 31, 12, p. 1356-1363

Research output: Contribution to journalArticle

File
2 Citations (Scopus)
38 Downloads (Pure)

Non-invasive, transdermal, path-selective and specific glucose monitoring via a graphene-based platform

Lipani, L., Dupont, B. G. R., Doungmene, F., Marken, F., Tyrrell, R. M., Guy, R. H. & Ilie, A., 30 Jun 2018, In : Nature Nanotechnology. 13, 6, p. 504-511 8 p.

Research output: Contribution to journalArticle

Open Access
File
66 Citations (Scopus)
553 Downloads (Pure)

Topical bio(in)equivalence of metronidazole formulations in vivo

Pedon de Araujo, T., Moura Fittipaldi, I., Galindo Bedor, D. C., Ludna Duarte, M., Cordery, S., Guy, R., Delgado-Charro, M., Pereira de Santana, D. & Bastos Leal, L., 25 Apr 2018, In : International Journal of Pharmaceutics. 541, 1-2, p. 167-172 6 p.

Research output: Contribution to journalArticle

Open Access
File
4 Citations (Scopus)
37 Downloads (Pure)
2017

Bioequivalence methodologies for topical drug products: in vitro and ex vivo studies with a cortiscosteroid and an anti-fungal drug

Bastos Leal, L., Cordery, S. F., Delgado-Charro, M. B., Bunge, A. L. & Guy, R. H., Apr 2017, In : Pharmaceutical Research. 34, 4, p. 730-737 8 p.

Research output: Contribution to journalArticle

Open Access
10 Citations (Scopus)

Precise laser poration to control drug delivery into and through human nail

Vanstone, S., Cordery, S., Stone, J., Gordeev, S. & Guy, R., 28 Dec 2017, In : Journal of Controlled Release. 268, p. 72-77 6 p.

Research output: Contribution to journalArticle

Open Access
File
6 Citations (Scopus)
159 Downloads (Pure)

Reverse iontophoretic extraction of metabolites from living plants and their identification by ion-chromatography coupled to high resolution mass spectrometry

Gonzalez-Sanchez, M. I., McCullagh, J., Guy, R. & Compton, R., May 2017, In : Phytochemical Analysis. 28, 3, p. 195-201 7 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Topical bioavailability of diclofenac from locally-acting, dermatological formulations

Cordery, S. F., Pensado, A., Chiu, W. S., Shehab, M. Z., Bunge, A. L., Delgado-Charro, M. B. & Guy, R. H., 30 Aug 2017, In : International Journal of Pharmaceutics. 529, 1-2, p. 55-64 10 p.

Research output: Contribution to journalArticle

Open Access
File
13 Citations (Scopus)
200 Downloads (Pure)
2016

Assessing the safety of cosmetic chemicals: consideration of a flux decision tree to predict dermally delivered systemic dose for comparison with oral TTC (Threshold of Toxicological Concern)

Williams, F. M., Rothe, H., Barrett, G., Chiodini, A., Whyte, J., Cronin, M. T. D., Monteiro-Riviere, N. A., Plautz, J., Roper, C., Westerhout, J., Yang, C. & Guy, R. H., 1 Apr 2016, In : Regulatory Toxicology and Pharmacology. 76, p. 174-186 13 p.

Research output: Contribution to journalArticle

Open Access
27 Citations (Scopus)

Choice of moisturiser for eczema treatment (COMET): feasibility study of a randomised controlled parallel group trial in children recruited from primary care

Ridd, M., Garfield, K., Gaunt, D., Hollinghurst, S., Redmond, N., Powell, K., Wilson, V., Guy, R., Ball, N., Shaw, L., Purdy, S. & Metcalfe, C., 16 Nov 2016, In : BMJ Open. 6, 11, 9 p., e012021.

Research output: Contribution to journalArticle

Open Access
12 Citations (Scopus)

Femtosecond pulsed laser ablation to enhance drug delivery across the skin

Garvie-Cook, H., Stone, J. M., Yu, F., Guy, R. H. & Gordeev, S. N., 5 Jan 2016, In : Journal of Biophotonics. 9, 1-2, p. 144-154 11 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)
Open Access
File
10 Citations (Scopus)
211 Downloads (Pure)

Managing diabetes through the skin: Diagnostic devices

Guy, R., Jun 2016, In : Nature Nanotechnology. 11, 6, p. 493-494 2 p.

Research output: Contribution to journalArticle

Open Access
File
12 Citations (Scopus)
170 Downloads (Pure)

Metals and the skin: Topical effects and systemic absorption

Guy, R. H., Hostýnek, J. J., Hinz, R. S. & Lorence, C. R., 19 Apr 2016, CRC Press. 431 p.

Research output: Book/ReportBook

4 Citations (Scopus)

Modelling drug flux through microporated skin

Rzhevskiy, A. S., Guy, R. H. & Anissimov, Y. G., 10 Nov 2016, In : Journal of Controlled Release. 241, p. 194-199 6 p.

Research output: Contribution to journalArticle

Open Access
File
6 Citations (Scopus)
135 Downloads (Pure)

The potential of polymeric film-forming systems as sustained delivery platforms for topical drugs

Frederiksen, K., Guy, R. H. & Petersson, K., 2016, In : Expert Opinion on Drug Delivery. 13, 3, p. 349-360

Research output: Contribution to journalArticle

Open Access
File
15 Citations (Scopus)
175 Downloads (Pure)
2015

Biophysical elucidation of the mechanism of enhanced drug release and topical delivery from polymeric film-forming systems

Garvie-Cook, H., Frederiksen, K., Petersson, K., Guy, R. & Gordeev, S., 28 Aug 2015, In : Journal of Controlled Release. 212, p. 103-112 10 p.

Research output: Contribution to journalArticle

Open Access
File
7 Citations (Scopus)
151 Downloads (Pure)

Characterization of Topical Film-Forming Systems Using Atomic Force Microscopy and Raman Microspectroscopy

Garvie-cook, H., Frederiksen, K., Petersson, K., Guy, R. H. & Gordeev, S., Mar 2015, In : Molecular Pharmaceutics. 12, 3, p. 751-757 7 p.

Research output: Contribution to journalArticle

Open Access
File
12 Citations (Scopus)
152 Downloads (Pure)

Choice of Moisturiser for Eczema Treatment (COMET): Study protocol for a randomized controlled trial

Ridd, M. J., Redmond, N. M., Hollinghurst, S., Ball, N., Shaw, L., Guy, R., Wilson, V., Metcalfe, C. & Purdy, S., 15 Jul 2015, In : Trials. 16, 304.

Research output: Contribution to journalArticle

Open Access
File
14 Citations (Scopus)
97 Downloads (Pure)

Development and in vitro evaluation of lipid nanoparticle-based dressings for topical treatment of chronic wounds

Gainza, G., Chu, W. S., Guy, R. H., Pedraz, J. L., Hernandez, R. M., Delgado-Charro, B. & Igartua, M., 25 Jul 2015, In : International Journal of Pharmaceutics. 490, 1-2, p. 404-411 8 p.

Research output: Contribution to journalArticle

File
19 Citations (Scopus)
148 Downloads (Pure)

Drug delivery into microneedle-porated nails from nanoparticle reservoirs

Chiu, W. S., Belsey, N. A., Garrett, N. L., Moger, J., Price, G. J., Delgado-Charro, M. B. & Guy, R. H., 28 Dec 2015, In : Journal of Controlled Release. 220, A, p. 98-106 9 p.

Research output: Contribution to journalArticle

Open Access
File
19 Citations (Scopus)
134 Downloads (Pure)
Open Access
File
31 Citations (Scopus)
251 Downloads (Pure)

In situ detection of salicylate in Ocimum basilicum plant leaves via reverse iontophoresis

González-Sánchez, M. I., Lee, P. T., Guy, R. H. & Compton, R. G., 28 Nov 2015, In : Chemical Communications. 51, 92, p. 16534-16536 3 p.

Research output: Contribution to journalArticle

Open Access
File
13 Citations (Scopus)
136 Downloads (Pure)

In vitro method to quantify dermal absorption of pesticide residues

Clarke, J. F., Cordery, S. F., Morgan, N. A., Knowles, P. K. & Guy, R. H., 16 Feb 2015, In : Chemical Research in Toxicology. 28, 2, p. 166-168

Research output: Contribution to journalArticle

Open Access
File
4 Citations (Scopus)
137 Downloads (Pure)

Iontophoresis of minoxidil sulphate loaded microparticles, a strategy for follicular drug targeting?

Gelfuso, G. M., Barros, M. A. D. O., Delgado-Charro, M. B., Guy, R. H. & Lopez, R. F. V., Oct 2015, In : Colloids and Surfaces B: Biointerfaces. 134, p. 408-412 5 p.

Research output: Contribution to journalArticle

Open Access
File
20 Citations (Scopus)
158 Downloads (Pure)

Iontophoretic transdermal sampling of iohexol as a noninvasive tool to assess glomerular filtration rate

Djabri, A., van’t Hoff, W., Brock, P., Wong, I. C. K., Guy, R. & Delgado-Charro, B., 1 Feb 2015, In : Pharmaceutical Research. 32, 2, p. 590-603 14 p.

Research output: Contribution to journalArticle

Open Access
File
3 Citations (Scopus)
142 Downloads (Pure)

Molecular diffusion in the human nail measured by stimulated Raman scattering microscopy

Chiu, W-S., Belsey, N., Garrett, N. L., Moger, J., Delgado-Charro, M. & Guy, R., 23 Jun 2015, In : Proceedings of the National Academy of Sciences of the United States of America. 112, 25, p. 7725-7730 6 p.

Research output: Contribution to journalArticle

Open Access
File
30 Citations (Scopus)
159 Downloads (Pure)
Open Access
File
10 Citations (Scopus)
148 Downloads (Pure)
2014
Open Access
File
30 Citations (Scopus)
189 Downloads (Pure)
Open Access
File
33 Citations (Scopus)
167 Downloads (Pure)

Characterisation of skin barrier function using bioengineering and biophysical techniques

Yang, Q. & Guy, R. H., 5 Aug 2014, In : Pharmaceutical Research. 32, 2, p. 445-457

Research output: Contribution to journalArticle

Open Access
File
7 Citations (Scopus)
168 Downloads (Pure)

Effective use of transdermal drug delivery in children

Delgado-Charro, M. B. & Guy, R. H., 30 Jun 2014, In : Advanced Drug Delivery Reviews. 73, p. 63-82

Research output: Contribution to journalReview article

File
46 Citations (Scopus)
229 Downloads (Pure)

Evaluation of drug delivery to intact and porated skin by coherent Raman scattering and fluorescence microscopies

Belsey, N. A., Garrett, N. L., Contreras-Rojas, L. R., Pickup-Gerlaugh, A. J., Price, G. J., Moger, J. & Guy, R. H., 28 Jan 2014, In : Journal of Controlled Release. 174, 28, p. 37-42 6 p.

Research output: Contribution to journalArticle

Open Access
File
42 Citations (Scopus)
214 Downloads (Pure)

Imaging drug delivery to skin with coherent raman scattering microscopy

Belsey, N. A., Contreras-Rojas, L. R. & Guy, R. H., 1 Jan 2014, Non Invasive Diagnostic Techniques in Clinical Dermatology. Springer Berlin Heidelberg, p. 225-231 7 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Serious photocontact dermatitis induced by topical ketoprofen depends on the formulation

Guy, R. H., Kuma, H. & Nakanishi, M., May 2014, In : European Journal of Dermatology. 24, 3, p. 365-371 7 p.

Research output: Contribution to journalArticle

Open Access
File
4 Citations (Scopus)
280 Downloads (Pure)

Transdermal drug delivery: 30 + years of war and still fighting!

Wiedersberg, S. & Guy, R. H., 28 Sep 2014, In : Journal of Controlled Release. 190, p. 150-156

Research output: Contribution to journalArticle

Open Access
File
117 Citations (Scopus)
262 Downloads (Pure)
2013
Open Access
File
9 Citations (Scopus)
144 Downloads (Pure)

Iontophoresis-targeted, follicular delivery of minoxidil sulfate for the treatment of alopecia

Gelfuso, G. M., Gratieri, T., Delgado-Charro, M. B., Guy, R. H. & Vianna Lopez, R. F., 1 May 2013, In : Journal of Pharmaceutical Sciences. 102, 5, p. 1488-1494

Research output: Contribution to journalArticle

24 Citations (Scopus)

Mechanical tomography of human corneocytes with a nanoneedle

Beard, J. D., Guy, R. H. & Gordeev, S. N., Jun 2013, In : Journal Of Investigative Dermatology. 133, 6, p. 1565-1571 7 p.

Research output: Contribution to journalArticle

Open Access
File
17 Citations (Scopus)
118 Downloads (Pure)

Method for non-invasively determining the relative levels of two biological substances. T3

Delgado-Charro, M. & Guy, R., 4 Feb 2013, Patent No. ES2394691T, Priority date 22 Jun 2001, Priority No. EP01114750

Research output: Patent

Products in "Bounty bags" potentially harm newborn skin

Ridd, M., Guy, R., Ball, N., Roberts, A. & Williams, H., 22 Jun 2013, In : BMJ . 346, 7913, f3895.

Research output: Contribution to journalArticle

Transdermal flux predictions for selected selective oestrogen receptor modulators (SERMs): Comparison with experimental results

Güngör, S., Delgado-Charro, M. B., Masini-Etévé, V., Potts, R. O. & Guy, R. H., 28 Dec 2013, In : Journal of Controlled Release. 172, 3, p. 601-606 6 p.

Research output: Contribution to journalArticle

Open Access
File
5 Citations (Scopus)
49 Downloads (Pure)
2012

Comparison of gravimetric and spectroscopic approaches to quantify stratum corneum removed by tape-stripping

Mohammed, D., Yang, Q., Guy, R. H., Matts, P. J., Hadgraft, J. & Lane, M. E., Sep 2012, In : European Journal of Pharmaceutics and Biopharmaceutics. 82, 1, p. 171-174

Research output: Contribution to journalArticle

32 Citations (Scopus)