Find Research Outputs

Search concepts
Selected filters
2019

A boronic acid-based fluorescent hydrogel for monosaccharide detection

Xu, S., Sedgwick, A. C., Elfeky, S. A., Chen, W., Jones, A. S., Williams, G. T., Jenkins, A. T. A., Bull, S. D., Fossey, J. S. & James, T. D., 21 May 2019, In : Frontiers of Chemical Science and Engineering.

Research output: Contribution to journalArticle

Open Access
2 Citations (Scopus)

A Selective Deprotection Strategy for the Construction of trans-2-Aminocyclopropanecarboxylic Acid Derived Peptides

Boddaert, T., Taylor, J. E., Bull, S. D. & Aitken, D. J., 4 Jan 2019, In : Organic Letters. 21, 1, p. 100-103 4 p.

Research output: Contribution to journalArticle

Open Access
File
2 Citations (Scopus)
3 Downloads (Pure)

Continuous-flow liquid-phase dehydrogenation of 1,4-cyclohexanedione in a structured multichannel reactor

Ashraf, M. A., Tan, J., Davidson, M. G., Bull, S., Hutchby, M., Mattia, D. & Plucinski, P., 1 Jan 2019, In : Reaction Chemistry & Engineering. 4, 1, p. 27-40 14 p.

Research output: Contribution to journalArticle

Open Access
File
Open Access

Coumarin-based fluorescent 'AND' logic gate probes for the detection of homocysteine and a chosen biological analyte

Wu, L., Gardiner, J. E., Kumawat, L. K., Han, H. H., Guo, R., Li, X., He, X. P., Elmes, R. B. P., Sedgwick, A. C., Bull, S. D. & James, T. D., 27 Aug 2019, In : RSC Advances. 9, 45, p. 26425-26428 4 p.

Research output: Contribution to journalArticle

Open Access
2 Citations (Scopus)

Dual enzyme activated fluorescein based fluorescent probe

Odyniec, M. L., Gardiner, J. E., Sedgwick, A. C., He, X. P., Bull, S. D. & James, T. D., 1 Mar 2019, In : Frontiers of Chemical Science and Engineering.

Research output: Contribution to journalArticle

Open Access

Dynamic stall alleviation through mini-tabs

Bull, S. C., Chiereghin, N., Gursul, I. & Cleaver, D. J., 6 Jan 2019, AIAA Scitech 2019 Forum. American Institute of Aeronautics and Astronautics Inc.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

2 Citations (Scopus)

ESIPT-based fluorescence probe for the ratiometric detection of superoxide

Wu, L., Liu, L., Han, H. H., Tian, X., Odyniec, M. L., Feng, L., Sedgwick, A. C., He, X. P., Bull, S. D. & James, T. D., 21 Feb 2019, In : New Journal of Chemistry. 43, 7, p. 2875-2877 3 p.

Research output: Contribution to journalArticle

Open Access
17 Downloads (Pure)

Exposing the Interplay Between Enzyme Turnover, Protein Dynamics and the Membrane Environment in Monoamine Oxidase B

Jones, H. B. L., Crean, R. M., Mullen, A., Kendrick, E., Bull, S. D., Wells, S. A., Carbery, D. R., MacMillan, F., van der Kamp, M. W. & Pudney, C. R., 7 May 2019, In : Biochemistry. 58, 18, p. 2362-2372 11 p.

Research output: Contribution to journalArticle

Open Access
File
1 Citation (Scopus)

Long Wavelength TCF-Based Fluorescent Probe for the Detection of Alkaline Phosphatase in Live Cells

Gwynne, L., Sedgwick, A. C., Gardiner, J. E., Williams, G. T., Kim, G., Maillard, J. Y., Jenkins, T., Bull, S. D., Sessler, J. L., Yoon, J. & James, T. D., 30 Apr 2019, In : Frontiers in Chemistry. 7, APR, p. 1-6 6 p., 255.

Research output: Contribution to journalArticle

Open Access

METHOD OF DETECTING PEROXYNITRITE USING A COMPLEX OF A SACCHARIDE AND AN ARYLBORONATE-BASED FLUORESCENT PROBE

James, T., Bull, S. & Sun, X., 2019, Patent No. WO 2015/128622 (EP3110827, US2017059573), 24 Feb 2015, Priority date 27 Feb 2014, Priority No. 1403470.6

Research output: Patent

Reaction-Based Fluorescent Probes for the Detection and Imaging of Reactive Oxygen, Nitrogen, and Sulfur Species

Wu, L., Sedgwick, A. C., Sun, X., Bull, S. D., He, X. P. & James, T. D., 17 Sep 2019, In : Accounts of Chemical Research. 52, 9, p. 2582-2597 16 p.

Research output: Contribution to journalArticle

Open Access

Reaction-based indicator displacement assay (RIA) for the development of a triggered release system capable of biofilm inhibition

Patenall, B. L., Williams‡, G. T., Gwynne, L., Stephens, L. J., Lampard, E. V., Hathaway, H. J., Thet, N. T., Young, A. E., Sutton, M. J., Short, R. D., Bull, S. D., James, T. D., Sedgwick, A. C. & Jenkins, A. T. A., 12 Dec 2019, In : Chemical Communications. 55, 100, p. 15129-15132 4 p.

Research output: Contribution to journalArticle

Open Access

Voltammetric Monitoring of a Solid-Liquid Phase Transition in N,N,N’,N’-Tetraoctyl-2,6-diamino-9,10-anthraquinone (TODAQ)

Marken, F., Jones, M., Ahn, S. Y., Forder, T., Blackburn, R., Fordred, P. & Bull, S., 13 Nov 2019, (Accepted/In press) In : Journal of Solid State Electrochemistry.

Research output: Contribution to journalArticle

2018
2 Citations (Scopus)
19 Downloads (Pure)

1,1-Diacyloxy-1-phenylmethanes as versatile N-acylating agents for amines

Chapman, R. S. L., Tibbetts, J. D. & Bull, S. D., 20 Sep 2018, In : Tetrahedron. 74, 38, p. 5330-5339 10 p.

Research output: Contribution to journalArticle

Open Access
File
Aniline Compounds
Amides
Amines
1 Citation (Scopus)

A happy couple

Marken, F. & Bull, S. D., 1 Jul 2018, In : Nature Catalysis. 1, 7, p. 484-485 2 p.

Research output: Contribution to journalShort survey

Palladium
Catalysis
Sustainable development
Anodes
Electrodes
11 Citations (Scopus)

'AND'-based fluorescence scaffold for the detection of ROS/RNS and a second analyte

Odyniec, M. L., Sedgwick, A. C., Swan, A. H., Weber, M., Tang, T. M. S., Gardiner, J. E., Zhang, M., Jiang, Y. B., Kociok-Kohn, G., Elmes, R. B. P., Bull, S. D., He, X. P. & James, T. D., 27 Jun 2018, In : Chemical Communications. 54, p. 8466-8469 4 p.

Research output: Contribution to journalArticle

Open Access
Scaffolds
Fluorescence
Biomarkers
Esterases
Fluorescent Dyes
25 Citations (Scopus)

An ESIPT Probe for the Ratiometric Imaging of Peroxynitrite Facilitated by Binding to Aβ-Aggregates

Sedgwick, A. C., Dou, W. T., Jiao, J. B., Wu, L., Williams, G. T., Jenkins, A. T. A., Bull, S. D., Sessler, J. L., He, X. P. & James, T. D., 31 Oct 2018, In : Journal of the American Chemical Society. 140, 43, p. 14267-14271 5 p.

Research output: Contribution to journalArticle

Open Access
5 Citations (Scopus)
20 Downloads (Pure)

A simple umbelliferone based fluorescent probe for the detection of nitroreductase

Sedgwick, A. C., Hayden, A., Hill, B., Bull, S. D., Elmes, R. B. P. & James, T. D., 1 Jun 2018, In : Frontiers of Chemical Science and Engineering. 12, 2, p. 311-314 4 p.

Research output: Contribution to journalArticle

Open Access
File
7-hydroxycoumarin
Nitroreductases
Fluorescent Dyes
Enzymes
Fluorophores
8 Citations (Scopus)

Boronate-Based Fluorescence Probes for the Detection of Hydrogen Peroxide

Lampard, E. V., Sedgwick, A. C., Sun, X., Filer, K. L., Hewins, S. C., Kim, G., Yoon, J., Bull, S. D. & James, T. D., 1 Mar 2018, In : ChemistryOpen. 7, 3, p. 262-265 4 p.

Research output: Contribution to journalArticle

Open Access

Correction: A bodipy based hydroxylamine sensor (Chemical Communications (2017) 53 (10441-10443) DOI: 10.1039/C7CC05872A)

Sedgwick, A. C., Chapman, R. S. L., Gardiner, J. E., Peacock, L. R., Kim, G., Yoon, J., Bull, S. D. & James, T. D., 4 Oct 2018, In : Chemical Communications. 54, 77, p. 10922 1 p.

Research output: Contribution to journalArticle

Open Access

Correction: Boronate based fluorescence (ESIPT) probe for peroxynitrite(Chem. Commun. (2016) 52 (12350–12352) DOI: 10.1039/C6CC06829D)

Sedgwick, A. C., Sun, X., Kim, G., Yoon, J., Bull, S. D. & James, T. D., 28 Sep 2018, In : Chemical Communications. 54, 76, p. 10775 1 p.

Research output: Contribution to journalArticle

Open Access
14 Citations (Scopus)
29 Downloads (Pure)

Dual-function cellulose composites for fluorescence detection and removal of fluoride

Li, M., Liu, Z., Wang, H. C., Sedgwick, A. C., Gardiner, J. E., Bull, S. D., Xiao, H. N. & James, T. D., 1 Feb 2018, In : Dyes and Pigments. 149, p. 669-675 7 p.

Research output: Contribution to journalArticle

Open Access
File
Fluorides
Cellulose
Fluorescence
Adsorption
Composite materials
2 Citations (Scopus)

Dye Displacement Assay for Saccharides using Benzoxaborole Hydrogels

Lampard, E. V., Sedgwick, A. C., Sombuttan, T., Williams, G. T., Wannalerse, B., Jenkins, A. T. A., Bull, S. D. & James, T. D., 1 Mar 2018, In : ChemistryOpen. 7, 3, p. 266-268 3 p.

Research output: Contribution to journalArticle

Open Access
Hydrogels
Assays
Coloring Agents
Boronic Acids
Monosaccharides
18 Downloads (Pure)

Electrochemically Driven C-H Hydrogen Abstraction Processes with the Tetrachloro-Phthalimido-N-Oxyl (Cl4PINO) Catalyst

Marken, F., Buckingham, M. A., Bull, S., Cunningham, W., Buchard, A., Folli, A. & Murphy, D., 1 Aug 2018, In : Electroanalysis. 30, 8, p. 1706-1713 8 p.

Research output: Contribution to journalArticle

Open Access
File
Hydrogen
Alcohols
Catalysts
Rate constants
Oxidation
26 Citations (Scopus)

ESIPT-based fluorescence probe for the rapid detection of hypochlorite (HOCl/ClO-)

Wu, L., Yang, Q., Liu, L., Sedgwick, A. C., Cresswell, A. J., Bull, S. D., Huang, C. & James, T. D., 4 Jul 2018, In : Chemical Communications. 54, 61, p. 8522-8525 4 p.

Research output: Contribution to journalArticle

Open Access
Hypochlorous Acid
Fluorescence
Water
Logic gates
Potable water
12 Citations (Scopus)

ESIPT-based fluorescence probe for the rapid detection of peroxynitrite ‘AND' biological thiols

Wu, L., Han, H. H., Liu, L., Gardiner, J. E., Sedgwick, A. C., Huang, C., Bull, S. D., He, X. P. & James, T. D., 14 Oct 2018, In : Chemical Communications. 54, 80, p. 11336-11339 4 p.

Research output: Contribution to journalArticle

Open Access
21 Citations (Scopus)

ESIPT-based ratiometric fluorescence probe for the intracellular imaging of peroxynitrite

Wu, L., Wang, Y., Weber, M., Liu, L., Sedgwick, A. C., Bull, S. D., Huang, C. & James, T. D., 7 Aug 2018, In : Chemical Communications. 54, 71, p. 9953-9956 4 p.

Research output: Contribution to journalArticle

Open Access
Peroxynitrous Acid
Fluorescent Dyes
Fluorescence
Imaging techniques
Experiments
110 Citations (Scopus)

Excited-state intramolecular proton-transfer (ESIPT) based fluorescence sensors and imaging agents

Sedgwick, A. C., Wu, L., Han, H. H., Bull, S. D., He, X. P., James, T. D., Sessler, J. L., Tang, B. Z., Tian, H. & Yoon, J., 26 Nov 2018, In : Chemical Society Reviews. 47, 23, p. 8842-8880 39 p.

Research output: Contribution to journalReview article

Open Access
11 Citations (Scopus)
29 Downloads (Pure)
Open Access
File
Peroxynitrous Acid
Macrophages
Reactive Oxygen Species
Fluorescence
Oxidative stress
1 Citation (Scopus)

Formyloxyacetoxyphenylmethane and 1,1-diacylals as versatile O-formylating and O-acylating reagents for alcohols

Chapman, R., Francis, M., Lawrence, R., Tibbetts, J. & Bull, S., 1 Nov 2018, In : Tetrahedron. 74, 44, p. 6442-6452 11 p.

Research output: Contribution to journalArticle

20 Citations (Scopus)

Long-wavelength TCF-based fluorescence probes for the detection and intracellular imaging of biological thiols

Sedgwick, A. C., Gardiner, J. E., Kim, G., Yevglevskis, M., Lloyd, M. D., Jenkins, A. T. A., Bull, S. D., Yoon, J. & James, T. D., 11 May 2018, In : Chemical Communications. 54, 38, p. 4786-4789 4 p.

Research output: Contribution to journalArticle

Open Access
Sulfhydryl Compounds
Toxicity
Fluorescence
Drug therapy
Imaging techniques
34 Citations (Scopus)

The development of a novel AND logic based fluorescence probe for the detection of peroxynitrite and GSH

Sedgwick, A. C., Han, H. H., Gardiner, J. E., Bull, S. D., He, X-P. & James, T. D., 21 Apr 2018, In : Chemical Science. 9, 15, p. 3672-3676 5 p.

Research output: Contribution to journalArticle

Open Access
Peroxynitrous Acid
Fluorescence
Fluorescein
Imaging techniques
Experiments
2 Citations (Scopus)
36 Downloads (Pure)

Uncovering the relationship between the change in heat capacity for enzyme catalysis and vibrational frequency through isotope effect studies

Jones, H. B. L., Crean, R. M., Matthews, C., Troya, A. B., Danson, M. J., Bull, S. D., Arcus, V. L., Van Der Kamp, M. W. & Pudney, C. R., 1 Jun 2018, In : ACS Catalysis. 8, 6, p. 5340-5349 10 p.

Research output: Contribution to journalArticle

Open Access
File
Vibrational spectra
Isotopes
Catalysis
Specific heat
Substitution reactions
2017
18 Citations (Scopus)

A bodipy based hydroxylamine sensor

Sedgwick, A. C., Chapman, R. S. L., Gardiner, J. E., Peacock, L. R., Kim, G., Yoon, J., Bull, S. D. & James, T. D., 25 Sep 2017, In : Chemical Communications. 53, 75, p. 10441-10443

Research output: Contribution to journalArticle

Open Access
Hydroxylamine
Fluorescence
Sensors
9 Citations (Scopus)

Automation of route identification and optimisation based on data-mining and chemical intuition

Lapkin, A. A., Heer, P. K., Jacob, P. M., Hutchby, M., Cunningham, W., Bull, S. D. & Davidson, M. G., 1 Sep 2017, In : Faraday Discussions. 202, p. 483-496 14 p.

Research output: Contribution to journalArticle

Open Access
data mining
automation
Data mining
Identification (control systems)
Automation
27 Citations (Scopus)

Azulene–boronate esters: colorimetric indicators for fluoride in drinking water

Lopez-Alled, C. M., Sanchez Fernandez, A., Edler, K., Sedgwick, A., Bull, S., McMullin, C., Kociok-Kohn, G., James, T., Wenk, J. & Lewis, S., 4 Dec 2017, In : Chemical Communications. 53, 93, p. 12580-12583 4 p.

Research output: Contribution to journalArticle

Open Access
Fluorides
Developing countries
Potable water
Drinking Water
Esters
8 Citations (Scopus)
66 Downloads (Pure)

Formyloxyacetoxyphenylmethane as an N-Formylating Reagent for Amines, Amino Acids, and Peptides

Chapman, R., Lawrence, R., Williams, J. & Bull, S., 30 Aug 2017, p. 4908-4911.

Research output: Contribution to conferencePaper

Open Access
File
Formamides
Cyanides
Amines
Amino Acids
Peptides
42 Citations (Scopus)

Long-wavelength fluorescent boronate probes for the detection and intracellular imaging of peroxynitrite

Sedgwick, A. C., Han, H. H., Gardiner, J. E., Bull, S. D., He, X-P. & James, T. D., 11 Dec 2017, In : Chemical Communications. 53, 95, p. 12822-12825

Research output: Contribution to journalArticle

Open Access
Mitochondria
Peroxynitrous Acid
Solubility
Imaging techniques
Wavelength
9 Citations (Scopus)

Rapid determination of enantiomeric excess via NMR spectroscopy: A research-informed experiment

Fossey, J. S., Anslyn, E. V., Brittain, W. D. G., Bull, S. D., Chapin, B. M., Le Duff, C. S., James, T. D., Lees, G., Lim, S., Lloyd, J. A. C., Manville, C. V., Payne, D. T. & Roper, K. A., 10 Jan 2017, In : Journal of Chemical Education. 94, 1, p. 79-84 6 p.

Research output: Contribution to journalArticle

Open Access
Nuclear magnetic resonance spectroscopy
experiment
Experiments
Teaching
chemistry
11 Citations (Scopus)

Reaction-based indicator displacement assay (RIA) for the colorimetric and fluorometric detection of hydrogen peroxide

Sun, X., Odyniec, M. L., Sedgwick, A. C., Lacina, K., Xu, S., Qiang, T., Bull, S. D., Marken, F. & James, T. D., 1 Jun 2017, In : Organic Chemistry Frontiers. 4, 6, p. 1058-1062 5 p.

Research output: Contribution to journalArticle

Open Access
Hydrogen Peroxide
Assays
Phenol
Complexation
Fluorescence
2016
4 Citations (Scopus)
85 Downloads (Pure)

A Protocol for NMR Analysis of the Enantiomeric Excess of Chiral Diols Using an Achiral Diboronic Acid Template

Tickell, D. A., Lampard, E. V., Lowe, J. P., James, T. D. & Bull, S. D., 6 Jul 2016, In : Journal of Organic Chemistry. 81, 15, p. 6795–6799

Research output: Contribution to journalArticle

Open Access
File
Spectroscopic analysis
Esters
Nuclear magnetic resonance
Acids
14 Citations (Scopus)

Aza-conjugate addition methodology for the synthesis of N-hydroxy-isoindolin-1-ones

Royo, S., Chapman, R. S. L., Sim, A. M., Peacock, L. R. & Bull, S. D., 4 Mar 2016, In : Organic Letters. 18, 5, p. 1146-1149 4 p.

Research output: Contribution to journalArticle

Isoindoles
Hydroxylamine
Addition reactions
aldehydes
Aldehydes
62 Citations (Scopus)

Boronate based fluorescence (ESIPT) probe for peroxynitrite

Sedgwick, A., Sun, X., Kim, G., Yoon, J., Bull, S. D. & James, T. D., 25 Oct 2016, In : Chemical Communications. 52, 83, p. 12350-12352 3 p.

Research output: Contribution to journalArticle

Open Access
Peroxynitrous Acid
Fluorescence
Esters
Imaging techniques
Experiments
8 Citations (Scopus)

DBN hexafluorophosphate salts as convenient sulfonylating and phosphonylating agents

Jones, C. S., Bull, S. D. & Williams, J. M. J., 28 Sep 2016, In : Organic and Biomolecular Chemistry. 14, 36, p. 8452-8456 5 p.

Research output: Contribution to journalArticle

esters
Esters
Salts
salts
Organophosphonates
4 Citations (Scopus)
71 Downloads (Pure)

Hydrodynamic rocking disc electrode study of the TEMPO-mediated catalytic oxidation of primary alcohols

Ahn, S. Y., Fisher, A. C., Buchard, A., Bull, S. D., Bond, A. M. & Marken, F., Sep 2016, In : Electroanalysis. 28, 9, p. 2093-2103

Research output: Contribution to journalArticle

Open Access
File
Catalytic oxidation
Alcohols
Hydrodynamics
Electrodes
Rate constants
7 Citations (Scopus)

Orthogonally protected Schöllkopf’s bis-lactim ethers for the asymmetric synthesis of α-amino acid derivatives and dipeptide esters

Hutchby, M., Sedgwick, A. C. & Bull, S. D., Jul 2016, In : Synthesis. 48, 13, p. 2036-2049

Research output: Contribution to journalArticle

Ethers
Dipeptides
Alkylation
Hydrogenation
Amino acids