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  • 2019
  • 2017
  • 2016

Author

  • Barry Potter

The "other" inositols and their phosphates: synthesis, biology, and medicine (with recent advances in myo-inositol chemistry)

Thomas, M. P., Mills, S. J. & Potter, B. V. L., 26 Jan 2016, In : Angewandte Chemie-International Edition. 55, 5, p. 1614-1650

Research output: Contribution to journalArticle

62 Citations (Scopus)

Synthesis of Terminal Ribose Analogues of Adenosine 5′-Diphosphate Ribose as Probes for the Transient Receptor Potential Cation Channel TRPM2

Potter, B., Watt, J. M. & Baszczynski, O., 17 May 2019, In : Journal of Organic Chemistry. 84, 10, p. 6143-6157 15 p.

Research output: Contribution to journalArticle

Open Access
File
6 Citations (Scopus)
16 Downloads (Pure)

Simple synthesis of 32P-labelled inositol hexakisphosphates for study of phosphate transformations

Whitfield, H., Riley, A. M., Diogenous, S., Godage, H. Y., Potter, B. & Brearley, C. A., 27 Jun 2017, In : Plant and Soil.

Research output: Contribution to journalArticle

Open Access
4 Citations (Scopus)

SHIP2: structure, function and inhibition

Thomas, M. P., Erneux, C. & Potter, B. V. L., 1 Feb 2017, In : ChemBiochem. 18, 3, p. 233-247

Research output: Contribution to journalArticle

Open Access
File
13 Citations (Scopus)
289 Downloads (Pure)

Second messenger analogues highlight unexpected substrate sensitivity of CD38: total synthesis of the hybrid “L-cyclic inosine 5'-diphosphate ribose”

Watt, J. M., Graeff, R., Thomas, M. P. & Potter, B., 23 Nov 2017, In : Scientific Reports. 7, 16100.

Research output: Contribution to journalArticle

Open Access
File
1 Citation (Scopus)
39 Downloads (Pure)

Ligand induced activation of human TRPM2 requires the terminal ribose of ADPR and involves Arg 1433 and Tyr 1349

Fliegert, R., Watt, J. M., Schöbel, A., Rozewitz, M. D., Moreau, C., Kirchberger, T., Thomas, M. P., Sick, W., Araujo, A. C., Harneit, A., Potter, B. V. L. & Guse, A. H., 16 Jun 2017, In : Biochemical Journal. 474, 13, p. 2159-2175 BCJ20170091.

Research output: Contribution to journalArticle

Open Access
15 Citations (Scopus)

Insights into the activation mechanism of class I HDAC complexes by inositol phosphates

Watson, P. J., Millard, C. J., Riley, A. M., Robertson, N. S., Wright, L. C., Godage, H. Y., Cowley, S. M., Jamieson, A. G., Potter, B. V. L. & Schwabe, J. W. R., 25 Apr 2016, In : Nature Communications. 7, 11262.

Research output: Contribution to journalArticle

Open Access
File
76 Citations (Scopus)
148 Downloads (Pure)

Different substrate specificities of the two ADPR binding sites in TRPM2 channels of Nematostella vectensis and the role of IDPR

Kühn, F. J. P., Watt, J. M., Potter, B. V. L. & Lückhoff, A., 21 Mar 2019, In : Scientific Reports. 9, 1, p. 1-12 12 p., 4985.

Research output: Contribution to journalArticle

Open Access
8 Citations (Scopus)

Crystal structures of type-II inositol polyphosphate 5-phosphatase INPP5B with synthetic inositol polyphosphate surrogates reveal new mechanistic insights for the inositol 5-phosphatase family

Mills, S. J., Silvander, C., Cozier, G., Trésaugues, L., Nordlund, P. & Potter, B. V. L., 8 Mar 2016, In : Biochemistry. 55, 9, p. 1384-1397

Research output: Contribution to journalArticle

Open Access
File
5 Citations (Scopus)
137 Downloads (Pure)

A Small Molecule Inhibitor of PDK1/PLCγ1 Interaction Blocks Breast and Melanoma Cancer Cell Invasion

Raimondi, C., Calleja, V., Ferro, R., Fantin, A., Riley, A. M., Potter, B. V. L., Brennan, C. H., Maffucci, T., Larijani, B. & Falasca, M., 20 May 2016, In : Scientific Reports. 6, 26142.

Research output: Contribution to journalArticle

Open Access
File
15 Citations (Scopus)
92 Downloads (Pure)
Open Access
3 Citations (Scopus)

2ʹ-Deoxyadenosine 5ʹ-diphosphoribose is an endogenous TRPM2 superagonist

Fliegert, R., Bauche, A., Wolf Pérez, A-M., Watt, J. M., Rozewitz, M. D., Winzer, R., Janus, M., Gu, F., Rosche, A., Harneit, A., Flato, M., Moreau, C., Kirchberger, T., Wolters, V., Potter, B. V. L. & Guse, A. H., 1 Sep 2017, In : Nature Chemical Biology. 13, p. 1036-1044 9 p.

Research output: Contribution to journalArticle

Open Access
File
27 Citations (Scopus)
168 Downloads (Pure)