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Author

  • Richard Guy
2016

The potential of polymeric film-forming systems as sustained delivery platforms for topical drugs

Frederiksen, K., Guy, R. H. & Petersson, K., 2016, In : Expert Opinion on Drug Delivery. 13, 3, p. 349-360

Research output: Contribution to journalArticle

Open Access
File
19 Citations (Scopus)
191 Downloads (Pure)
2017

Precise laser poration to control drug delivery into and through human nail

Vanstone, S., Cordery, S., Stone, J., Gordeev, S. & Guy, R., 28 Dec 2017, In : Journal of Controlled Release. 268, p. 72-77 6 p.

Research output: Contribution to journalArticle

Open Access
File
6 Citations (Scopus)
173 Downloads (Pure)

Bioequivalence methodologies for topical drug products: in vitro and ex vivo studies with a cortiscosteroid and an anti-fungal drug

Bastos Leal, L., Cordery, S. F., Delgado-Charro, M. B., Bunge, A. L. & Guy, R. H., Apr 2017, In : Pharmaceutical Research. 34, 4, p. 730-737 8 p.

Research output: Contribution to journalArticle

Open Access
10 Citations (Scopus)
2013
Open Access
File
9 Citations (Scopus)
156 Downloads (Pure)
2019

Potential of iontophoresis as a drug delivery method for midazolam in pediatrics

Djabri, A., Guy, R. & Delgado-Charro, M., 1 Feb 2019, In : European Journal of Pharmaceutical Sciences. 128, p. 137-143 7 p.

Research output: Contribution to journalArticle

Open Access
File
2 Citations (Scopus)
35 Downloads (Pure)
2011

Imaging drug delivery to skin with stimulated Raman scattering microscopy

Saar, B. G., Contreras-Rojas, L. R., Xie, X. S. & Guy, R. H., 6 Jun 2011, In : Molecular Pharmaceutics. 8, 3, p. 969-975 7 p.

Research output: Contribution to journalArticle

Open Access
File
116 Citations (Scopus)
179 Downloads (Pure)
2015

Development and in vitro evaluation of lipid nanoparticle-based dressings for topical treatment of chronic wounds

Gainza, G., Chu, W. S., Guy, R. H., Pedraz, J. L., Hernandez, R. M., Delgado-Charro, B. & Igartua, M., 25 Jul 2015, In : International Journal of Pharmaceutics. 490, 1-2, p. 404-411 8 p.

Research output: Contribution to journalArticle

File
19 Citations (Scopus)
164 Downloads (Pure)

In situ detection of salicylate in Ocimum basilicum plant leaves via reverse iontophoresis

González-Sánchez, M. I., Lee, P. T., Guy, R. H. & Compton, R. G., 28 Nov 2015, In : Chemical Communications. 51, 92, p. 16534-16536 3 p.

Research output: Contribution to journalArticle

Open Access
File
13 Citations (Scopus)
147 Downloads (Pure)
2014

Imaging drug delivery to skin with coherent raman scattering microscopy

Belsey, N. A., Contreras-Rojas, L. R. & Guy, R. H., 1 Jan 2014, Non Invasive Diagnostic Techniques in Clinical Dermatology. Springer Berlin Heidelberg, p. 225-231 7 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

2018

Comparison of patient (POEM), observer (EASI, SASSAD, TIS) and corneometry measures of emollient effectiveness in children with eczema: findings from the COMET feasibility trial

Ridd, M. J., Gaunt, D. M., Guy, R. H., Redmond, N. M., Garfield, K., Hollinghurst, S., Ball, N., Shaw, L., Purdy, S. & Metcalfe, C., 1 Aug 2018, In : British Journal of Dermatology. 179, 2, p. 362-370 9 p.

Research output: Contribution to journalArticle

Open Access
File
2 Citations (Scopus)
45 Downloads (Pure)
2011

AFM nanotools for surgery of biological Cells

Beard, J. D., Gordeev, S. N. & Guy, R. H., 2011, In : Journal of Physics: Conference Series. 286, 1, 012003.

Research output: Contribution to journalArticle

1 Citation (Scopus)
2013

Products in "Bounty bags" potentially harm newborn skin

Ridd, M., Guy, R., Ball, N., Roberts, A. & Williams, H., 22 Jun 2013, In : BMJ . 346, 7913, f3895.

Research output: Contribution to journalArticle

2011

Assessment of dermal exposure to pesticide residues during re-entry

Belsey, N. A., Cordery, S. F., Bunge, A. L. & Guy, R. H., 15 May 2011, In : Environmental Science & Technology. 45, 10, p. 4609-4615 7 p.

Research output: Contribution to journalArticle

Open Access
File
13 Citations (Scopus)
165 Downloads (Pure)
2015

Iontophoretic transdermal sampling of iohexol as a noninvasive tool to assess glomerular filtration rate

Djabri, A., van’t Hoff, W., Brock, P., Wong, I. C. K., Guy, R. & Delgado-Charro, B., 1 Feb 2015, In : Pharmaceutical Research. 32, 2, p. 590-603 14 p.

Research output: Contribution to journalArticle

Open Access
File
3 Citations (Scopus)
151 Downloads (Pure)
2016

Managing diabetes through the skin: Diagnostic devices

Guy, R., Jun 2016, In : Nature Nanotechnology. 11, 6, p. 493-494 2 p.

Research output: Contribution to journalArticle

Open Access
File
13 Citations (Scopus)
179 Downloads (Pure)

Ibuprofen delivery into and through the skin from novel oxidized cellulose-based gels and conventional topical formulations

Celebi, D., Edler, K., Scott, J. & Guy, R., 30 Nov 2016, In : International Journal of Pharmaceutics. 514, p. 238-243 6 p.

Research output: Contribution to journalArticle

Open Access
File
10 Citations (Scopus)
225 Downloads (Pure)
2015

Choice of Moisturiser for Eczema Treatment (COMET): Study protocol for a randomized controlled trial

Ridd, M. J., Redmond, N. M., Hollinghurst, S., Ball, N., Shaw, L., Guy, R., Wilson, V., Metcalfe, C. & Purdy, S., 15 Jul 2015, In : Trials. 16, 304.

Research output: Contribution to journalArticle

Open Access
File
14 Citations (Scopus)
102 Downloads (Pure)
2019

Stratum corneum sampling to assess bioequivalence between topical acyclovir products

Pensado-Lopez, A., Chiu, W. S., Cordery, S., Rantou, E., Bunge, A. L., Delgado-Charro, B. & Guy, R., 1 Dec 2019, In : Pharmaceutical Research. 36, 12, p. 180-196 16 p., 180.

Research output: Contribution to journalArticle

Open Access

The European Medicines Agency’s goals for regulatory science to 2025

Hines, P., Guy, R., Humphreys, A. & Papaluca-Amati, M., 3 Jun 2019, In : Nature Reviews Drug Discovery. 18, 6, p. 403-404 2 p.

Research output: Contribution to journalComment/debate

Open Access
File
6 Citations (Scopus)
25 Downloads (Pure)

Scanning the horizon: a systematic literature review of methodologies

Hines, P., Yu, L. H., Guy, R. & Papaluca-Amati, M., 27 May 2019, BMJ Open, 9, 5, p. e026764 9 p.

Research output: Contribution to specialist publicationArticle

Open Access
2 Citations (Scopus)
2015
Open Access
File
35 Citations (Scopus)
269 Downloads (Pure)
Open Access
File
10 Citations (Scopus)
160 Downloads (Pure)
2013

Mechanical tomography of human corneocytes with a nanoneedle

Beard, J. D., Guy, R. H. & Gordeev, S. N., Jun 2013, In : Journal Of Investigative Dermatology. 133, 6, p. 1565-1571 7 p.

Research output: Contribution to journalArticle

Open Access
File
18 Citations (Scopus)
127 Downloads (Pure)
2016

Femtosecond pulsed laser ablation to enhance drug delivery across the skin

Garvie-Cook, H., Stone, J. M., Yu, F., Guy, R. H. & Gordeev, S. N., 5 Jan 2016, In : Journal of Biophotonics. 9, 1-2, p. 144-154 11 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)
2013

Method for non-invasively determining the relative levels of two biological substances. T3

Delgado-Charro, M. & Guy, R., 4 Feb 2013, Patent No. ES2394691T, Priority date 22 Jun 2001, Priority No. EP01114750

Research output: Patent

2015

Iontophoresis of minoxidil sulphate loaded microparticles, a strategy for follicular drug targeting?

Gelfuso, G. M., Barros, M. A. D. O., Delgado-Charro, M. B., Guy, R. H. & Lopez, R. F. V., Oct 2015, In : Colloids and Surfaces B: Biointerfaces. 134, p. 408-412 5 p.

Research output: Contribution to journalArticle

Open Access
File
20 Citations (Scopus)
170 Downloads (Pure)
2014

Characterisation of skin barrier function using bioengineering and biophysical techniques

Yang, Q. & Guy, R. H., 5 Aug 2014, In : Pharmaceutical Research. 32, 2, p. 445-457

Research output: Contribution to journalArticle

Open Access
File
7 Citations (Scopus)
180 Downloads (Pure)
2011
File
5 Citations (Scopus)
152 Downloads (Pure)
2016

Metals and the skin: Topical effects and systemic absorption

Guy, R. H., Hostýnek, J. J., Hinz, R. S. & Lorence, C. R., 19 Apr 2016, CRC Press. 431 p.

Research output: Book/ReportBook

4 Citations (Scopus)
2018

Non-invasive, transdermal, path-selective and specific glucose monitoring via a graphene-based platform

Lipani, L., Dupont, B. G. R., Doungmene, F., Marken, F., Tyrrell, R. M., Guy, R. H. & Ilie, A., 30 Jun 2018, In : Nature Nanotechnology. 13, 6, p. 504-511 8 p.

Research output: Contribution to journalArticle

Open Access
File
75 Citations (Scopus)
595 Downloads (Pure)

Topical bio(in)equivalence of metronidazole formulations in vivo

Pedon de Araujo, T., Moura Fittipaldi, I., Galindo Bedor, D. C., Ludna Duarte, M., Cordery, S., Guy, R., Delgado-Charro, M., Pereira de Santana, D. & Bastos Leal, L., 25 Apr 2018, In : International Journal of Pharmaceutics. 541, 1-2, p. 167-172 6 p.

Research output: Contribution to journalArticle

Open Access
File
4 Citations (Scopus)
42 Downloads (Pure)

Dermal Absorption of Pesticide Residues

Clarke, J., Cordery, S., Morgan, N. A., Knowles, P. & Guy, R., 17 Dec 2018, In : Chemical Research in Toxicology. 31, 12, p. 1356-1363

Research output: Contribution to journalArticle

File
2 Citations (Scopus)
43 Downloads (Pure)
2015

Biophysical elucidation of the mechanism of enhanced drug release and topical delivery from polymeric film-forming systems

Garvie-Cook, H., Frederiksen, K., Petersson, K., Guy, R. & Gordeev, S., 28 Aug 2015, In : Journal of Controlled Release. 212, p. 103-112 10 p.

Research output: Contribution to journalArticle

Open Access
File
10 Citations (Scopus)
162 Downloads (Pure)
2017

Topical bioavailability of diclofenac from locally-acting, dermatological formulations

Cordery, S. F., Pensado, A., Chiu, W. S., Shehab, M. Z., Bunge, A. L., Delgado-Charro, M. B. & Guy, R. H., 30 Aug 2017, In : International Journal of Pharmaceutics. 529, 1-2, p. 55-64 10 p.

Research output: Contribution to journalArticle

Open Access
File
16 Citations (Scopus)
220 Downloads (Pure)
2014

Transdermal drug delivery: 30 + years of war and still fighting!

Wiedersberg, S. & Guy, R. H., 28 Sep 2014, In : Journal of Controlled Release. 190, p. 150-156

Research output: Contribution to journalArticle

Open Access
File
121 Citations (Scopus)
287 Downloads (Pure)
2019

Regulatory Science and Innovation Programme for Europe (ReScIPE): A proposed model

Hines, P. A., Guy, R. H., Brand, A., Humphreys, A. J. & Papaluca-Amati, M., 19 Aug 2019, In : British Journal Of Clinical Pharmacology. p. 1-6 6 p.

Research output: Contribution to journalArticle

Open Access
File
3 Citations (Scopus)
25 Downloads (Pure)
2015

Molecular diffusion in the human nail measured by stimulated Raman scattering microscopy

Chiu, W-S., Belsey, N., Garrett, N. L., Moger, J., Delgado-Charro, M. & Guy, R., 23 Jun 2015, In : Proceedings of the National Academy of Sciences of the United States of America. 112, 25, p. 7725-7730 6 p.

Research output: Contribution to journalArticle

Open Access
File
31 Citations (Scopus)
169 Downloads (Pure)

In vitro method to quantify dermal absorption of pesticide residues

Clarke, J. F., Cordery, S. F., Morgan, N. A., Knowles, P. K. & Guy, R. H., 16 Feb 2015, In : Chemical Research in Toxicology. 28, 2, p. 166-168

Research output: Contribution to journalArticle

Open Access
File
5 Citations (Scopus)
167 Downloads (Pure)
2013

Iontophoresis-targeted, follicular delivery of minoxidil sulfate for the treatment of alopecia

Gelfuso, G. M., Gratieri, T., Delgado-Charro, M. B., Guy, R. H. & Vianna Lopez, R. F., 1 May 2013, In : Journal of Pharmaceutical Sciences. 102, 5, p. 1488-1494

Research output: Contribution to journalArticle

25 Citations (Scopus)
2014
Open Access
File
31 Citations (Scopus)
209 Downloads (Pure)

Evaluation of drug delivery to intact and porated skin by coherent Raman scattering and fluorescence microscopies

Belsey, N. A., Garrett, N. L., Contreras-Rojas, L. R., Pickup-Gerlaugh, A. J., Price, G. J., Moger, J. & Guy, R. H., 28 Jan 2014, In : Journal of Controlled Release. 174, 28, p. 37-42 6 p.

Research output: Contribution to journalArticle

Open Access
File
43 Citations (Scopus)
230 Downloads (Pure)
2016

Modelling drug flux through microporated skin

Rzhevskiy, A. S., Guy, R. H. & Anissimov, Y. G., 10 Nov 2016, In : Journal of Controlled Release. 241, p. 194-199 6 p.

Research output: Contribution to journalArticle

Open Access
File
7 Citations (Scopus)
150 Downloads (Pure)

Choice of moisturiser for eczema treatment (COMET): feasibility study of a randomised controlled parallel group trial in children recruited from primary care

Ridd, M., Garfield, K., Gaunt, D., Hollinghurst, S., Redmond, N., Powell, K., Wilson, V., Guy, R., Ball, N., Shaw, L., Purdy, S. & Metcalfe, C., 16 Nov 2016, In : BMJ Open. 6, 11, 9 p., e012021.

Research output: Contribution to journalArticle

Open Access
12 Citations (Scopus)
2011

Transdermal delivery of a buprenorphine/naltrexone combination for the treatment of polydrug abuse

Taverner, A., Cordery, S., Husbands, S. M., Guy, R. H., Delgado-Charro, B. M. & Bailey, C. P., Jan 2011, In : Pharmacological Reports. 63, 1, p. 257 1 p.

Research output: Contribution to journalMeeting abstract

2015

Characterization of Topical Film-Forming Systems Using Atomic Force Microscopy and Raman Microspectroscopy

Garvie-cook, H., Frederiksen, K., Petersson, K., Guy, R. H. & Gordeev, S., Mar 2015, In : Molecular Pharmaceutics. 12, 3, p. 751-757 7 p.

Research output: Contribution to journalArticle

Open Access
File
13 Citations (Scopus)
169 Downloads (Pure)
2019

Mechanism of human nail poration by high-repetition-rate, femtosecond laser ablation

Vanstone, S., Stone, J., Gordeev, S. & Guy, R., 31 Oct 2019, In : Drug Delivery and Translational Research. 9, 5, p. 956–967 12 p.

Research output: Contribution to journalArticle

Open Access
2016

Assessing the safety of cosmetic chemicals: consideration of a flux decision tree to predict dermally delivered systemic dose for comparison with oral TTC (Threshold of Toxicological Concern)

Williams, F. M., Rothe, H., Barrett, G., Chiodini, A., Whyte, J., Cronin, M. T. D., Monteiro-Riviere, N. A., Plautz, J., Roper, C., Westerhout, J., Yang, C. & Guy, R. H., 1 Apr 2016, In : Regulatory Toxicology and Pharmacology. 76, p. 174-186 13 p.

Research output: Contribution to journalArticle

Open Access
30 Citations (Scopus)
2015

Drug delivery into microneedle-porated nails from nanoparticle reservoirs

Chiu, W. S., Belsey, N. A., Garrett, N. L., Moger, J., Price, G. J., Delgado-Charro, M. B. & Guy, R. H., 28 Dec 2015, In : Journal of Controlled Release. 220, A, p. 98-106 9 p.

Research output: Contribution to journalArticle

Open Access
File
21 Citations (Scopus)
149 Downloads (Pure)
2011

Optimisation of Cosolvent Concentration for Topical Drug Delivery III - Influence of Lipophilic Vehicles on Ibuprofen Permeation

Watkinson, R. M., Guy, R. H., Oliveira, G., Hadgraft, J. & Lane, M. E., 2011, In : Skin Pharmacology and Physiology. 24, 1, p. 22-26 5 p.

Research output: Contribution to journalArticle

24 Citations (Scopus)
2013

Transdermal flux predictions for selected selective oestrogen receptor modulators (SERMs): Comparison with experimental results

Güngör, S., Delgado-Charro, M. B., Masini-Etévé, V., Potts, R. O. & Guy, R. H., 28 Dec 2013, In : Journal of Controlled Release. 172, 3, p. 601-606 6 p.

Research output: Contribution to journalArticle

Open Access
File
6 Citations (Scopus)
54 Downloads (Pure)